Researchers have found that male and female brains respond in remarkably different ways to high-fat meals. Those differences in the brain lead to greater inflammation and increased health risks in males that indulge on fatty foods in comparison to females, a new study in mice shows. The findings may help to explain observed differences in obesity outcomes between women and men and suggest that dietary advice should be made more sex-specific.
Pregnancy. A woman needs to deposit vitamins and minerals in her fat reserves (higher body-fat % than men) for a successful pregnancy.
Aside: Paleo guys, you’ve got it right. Your diet is low poly-fat because men are better hunters and women are grazers (e.g. high fat nuts and dairy). We evolved accordingly.