Asians more prone to vision issues than Whites

Ah, genetics.

Don’t count on them taking over just yet, when they can’t shoot a gun.

“At the gene level, some genes such as SHISA6-DNAH9 have been shown to interact with education level and exhibit strong genetic effects for myopia among Asians with at least higher secondary education10. In the current study, we demonstrate that new genetic effects implicated in myopia development could be uncovered by studying interactions between genetic variants and education level.”

Psst! Heterogeneity means racial differences!

“High education level was associated with a twofold more myopic spherical equivalent in individuals of Asian as compared with European ancestry (Asians: β=−1.09 D, 95% CI: −1.20 to −0.98 D; Europeans: β=−0.49 D, 95% CI: −0.54 to −0.44 D; Fig. 1). Among Asian studies, we also observed heterogeneity of education effects for refractive error. The education effects on spherical equivalent in Singapore Chinese were significantly larger than that in other Asian studies (Singapore Chinese: β=−1.75 D, 95% CI: −1.92 to −1.58 D; other Asian cohorts: β=−0.60 D, 95% CI: −0.75 to −0.46 D).”

Asians are even distinct from one another.
Can the weeaboo supremacy crap.

“The JMA for spherical equivalent in 10,315 individuals from the Asians cohorts identified genome-wide significant association for three genes: AREG, GABRR1 and PDE10A (PJMA<5.0 × 10−8; Table 3 and Fig. 2b). SNP × education interaction effects associated with spherical equivalent were observed at all three loci, with genetic effects significantly larger within participants who had a higher level of education compared with those with a lower education level: AREG (rs12511037, βint=−0.89±0.14 D, Pint=6.87 × 10−11), GABRR1 (rs13215566, βint=−0.56±0.14 D, Pint=8.48 × 10−5) and PDE10A (rs12206610, βint=−0.72±0.13 D, Pint=2.32 × 10−8). The genotype and phenotype associations were highly significant in the higher education stratum

mfw intelligence is genetic

(main genetic effects, 1.97 × 10−10≤Pmain≤8.16 × 10−8) but were considerably weaker in the lower education stratum (0.008≤Pmain≤0.243). There was no evidence of inter-study heterogeneity at index SNPs within AREG, GABRR1 or PDE10A loci (Q-test: Phet≥0.122).
GABRR1 and PDE10A index SNPs were not associated with spherical equivalent in European samples, for either the JMA test, SNP main effect or SNP × education interaction (Table 3). AREG SNP rs12511037 was excluded in the meta-analysis of European studies after QC filtering; hence, a proxy SNP, rs1246413, in linkage disequilibrium (LD) with rs12511037 in Asians (r2=0.97) was tested but not associated with spherical equivalent (PJMA=0.527; Pint=0.176).

my genetics are my privilege

The meta-regression including study-level characteristics as covariates in the model confirmed the heterogeneity between populations of European and Asian ancestry (GABRR1: P=0.006; PDE10A: P=0.0419; Supplementary Table 4). For PDE10A, besides ethnicity, average spherical equivalent of each study also explained the inter-study heterogeneity for the interaction effects (P=0.025).”

Money shot!

It’s almost as if their culture wasn’t based around reading so much as rice farming?
As opposed to Europe, where most people could write their own name.


1. Be civil. 2. Be logical or fair. 3. Do not bore me.

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