Men lose Y-chromosome with age

https://www.sciencedaily.com/releases/2016/05/160523212527.htm
That’s why they die earlier.

Really.
Stop blaming women and ‘sexism’, we aren’t omnipotent gene meddlers.
Also, genetic proof of a male wall. LOL. An explanation to why so many middle-aged men suddenly look like lesbians.

[coughs in Bruce Jenner]

And there’s no way to reverse it, before the snake oil salesmen jump up with a solution that, if it worked, would make them a billionaire.

Nobel winner.

World famous.

Popping pills to get out of laziness is what lefties do.

Bold for the lazy.

Using new tools to analyze genetic variations that accumulate with age, we can help explain how sporadic diseases like cancer or Alzheimer’s manifest,” says first author Jan Dumanski.

One such postzygotic mutation found in the cells of biological males is the loss of the Y chromosome in a degree of blood cells. Loss of Y occurs in up to 17 percent of men and is more likely to be found in older men and men who smoke. This study expands on the idea that loss of Y, already a known risk factor for cancer (10.1038/ng.2966), could be a predictive biomarker for a wider range of poor health outcomes, specifically Alzheimer’s. Why loss of Y can be linked to an increased risk for disease remains unclear, but the authors speculate it has to do with reduced immune system performance.

They should look at age groups of men.

And diet.

IMHO.

The researchers looked at over 3,000 men to ascertain whether there was any predictive association between loss of Y in blood cells and Alzheimer’s disease. The participants came from three long-term studies that could provide regular blood samples: the European Alzheimer’s Disease Initiative, the Uppsala Longitudinal Study of Adult Men, and the Prospective Investigation of the Vasculature in Uppsala Seniors. Across the datasets, those with the highest fraction of blood cells without a Y chromosome were consistently more likely to be diagnosed with Alzheimer’s.

….Really more of an outcome of poor genetic health….

Did you test for aluminium?

Attempt chelation therapy?

Yeah, fuck the easy solution, blame the Y chromosome.

Like women don’t get it.

“Having loss of Y is not 100 percent predictive that you will have either cancer or Alzheimer’s,” Forsberg says, adding that there were men in the study who had the mutation and lived with no symptoms well into their 90s.

Were their fathers older or younger?

If paternal age is a factor in ANYTHING, it’s a risk factor for this.

Male chromosome plus mutation. Come on.

Men think they can fool women but white hairs on a ballsack don’t lie.

“But in the future, loss of Y in blood cells can become a new biomarker for disease risk and perhaps evaluation can make a difference in detecting and treating problems early.”

No shit.

Forsberg, Dumanski, and colleagues will next investigate the effect of loss of Y in larger cohorts and explore in greater detail how it confers risk for specific types of cancers and disease. They also plan to look at the cellular changes caused by loss of Y and how it affects different types of blood cells.The researchers looked at over 3,000 men to ascertain whether there was any predictive association between loss of Y in blood cells and Alzheimer’s disease. The participants came from three long-term studies that could provide regular blood samples: the European Alzheimer’s Disease Initiative, the Uppsala Longitudinal Study of Adult Men, and the Prospective Investigation of the Vasculature in Uppsala Seniors. Across the datasets, those with the highest fraction of blood cells without a Y chromosome were consistently more likely to be diagnosed with Alzheimer’s.”

Should look at heart disease, primary killer of American males.

But that’s none of my business.

If men aged well, they wouldn’t need to be on supplements.
Young men on supplements is just sad, like young women getting plastic surgery.
There’s no room to move. If you can’t be all that young, what are they going to do?
Our society treats aging like cancer, it’s ridiculous Boomer youth cult propaganda to sell them supplements like detox tea and testosterone ball rub. You can’t fool mother nature.

When they actually hit middle-age, they won’t be able to keep up with that crap anyway.
Imagine most of your shallow friends disappearing because you dropped the massive timesink of gym addiction.
The Ken Doll homoerotic gym attention bros look sad after about 40.

Plus bodybuilder types know there are two types of muscle: appearance and strength.
Guess which one they all go for?

The one that instantly converts to stubborn fat if they so much as look at a complex carbohydrate past 30.

The Johnny Bravo look is actually, industry secret, physically weak.

In a fight, any martial artist will tell you the bulk limits their range of motion like a fatty anyway.

All men need is a healthy range of light muscle, which women prefer but don’t require any supplement sales.
Light muscle also provides cognitive benefits with no musculoskeletal downsides, including sag and joint pain.
Bruce Lee could take a Henry Cavill any day of the week.

With the T&A they have a woman’s hourglass in profile, they gay.

At least, appealing to that market…..

6 responses to “Men lose Y-chromosome with age

  1. Bruce Lee could take a Henry Cavill, but not a Hafthór Björnsson.

    https://www.menshealth.com/uk/building-muscle/a755986/hafthor-bjornsson-game-of-thrones-the-mountain/

    One key takeaway “Perhaps it’s the genetic inheritance from Viking warriors that explains why Iceland’s athletes dominate strongman competitions and the CrossFit Games. Or why its menfolk live longer than any other – an average of 81.2 years.”

    Lee also died young, from complications of a weight-training injury.

    A better example from China is Bolo Yeung https://www.youtube.com/watch?v=YOX1kTTmmEc who was friends with Lee, and in his 70’s is unbelievably fit… Although to be fair to Lee, we don’t have an example of how someone like him would have aged, since he trained for quickness and speed vs. power (and was unmatched to this day).

    The problem most men have today is lack of training for competitive sports (especially combat sports), as this eliminates all “for show” training, everything must serve the competition or you will lose. Without that experience, men literally have no concept of what’s required to be truly fit. They look at how those with that experience train, and think they’re crazy.

1. Be civil. 2. Be logical or fair. 3. Do not bore me.

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