Behavioural genetics continues to rustle SJW jimmies

http://uk.businessinsider.com/genes-play-role-in-antisocial-personality-disorder-2016-9

role?

A role?

Yes, like water has a role in osmosis.

“And a new study has begun the task of identifying which genes are most likely involved in ASPD, with significant success.”

Please start on borderlines and histrionics and narcissists. We can clear Parliament. We can do it.
Suck on your socialization hypothesis.

“This seems to be the first time researchers have made this leap with a personality disorder.

But just as interesting are the concerns the researchers express about how their research might be misused. “

Here we go. The guilt-trip.
The findings stand by themselves, it is a choice how we use them.

…In the past, claims about specific genes and violence have been — in the researchers’ words — “misused” by prosecutors as evidence that defendants are violent. And as more studies like this one link specific genes to the potential for violence, that danger only grows.

It revokes neither legal agency (you chose to act on it) nor commits crime (the act) on its own grounds (that would be like arresting redheads). Being born isn’t a crime, they’re being misleading.
This is about racial profiling, among others. Prediction is the trigger word. They can’t say it shouldn’t be studied but they want to.

Some people have the brain structure of psychopaths – they are not psychopaths.
Some people have a blue-eye allele – they do not have blue eyes.

This is simply a filter for early on in the process that might save lives, like estimating their height from a footprint.

Also, the amused expression on this woman typifies the K-type reaction to violence.

http://uk.businessinsider.com/walmart-customer-posts-footage-of-fatal-shooting-2016-9

She wants the party to start already. I don’t post about Ks enough but they rarely make the news.

Link: Toxoplasma dumbs primates to threat

http://www.independent.co.uk/news/science/toxoplasma-gondii-parasite-that-breeds-in-cats-could-affect-human-behaviour-when-it-infects-people-a6861221.html

The part about “cysts on the amygdala” made me LOL.

really_house_of_cards

They don’t even call it what it is: brain damage. No bias there.

Can Islamic State send us urine samples?

Seriously though there is a huge methodological flaw. The studies look at prey species. Humans are no longer a prey species, we are inter-predatory. They should be studying how fear is modulated between categories of human. Since this is evolution, genetic geography would be a good proxy. The more foreign the source, the more aversion you’d expect.

Paper: Genetic dissection of sex differences in human brain and behaviour

http://discovery.ucl.ac.uk/1317810/1/1317810.pdf

Over 200 pages.

Abstract;

The importance of sex differences in the brain and behaviour is indisputable. It forms the basis for differences in risk across a range of neurological and psychiatric disorders, as well as gender roles within society. The classical approach to investigating sex differences primarily involves comparisons between males and females. While informative for characterizing the wide array of sexually dimorphic traits, straight comparisons are insufficient to elucidate specific molecular contributions due to the multiplicity of confounding factors. Discrete genetic polymorphisms can be used to investigate variance in these traits due to sex-related molecular factors independent of confounds of sex.
This thesis applies candidate genetics to understand the specific contributions of molecular components of the sex hormone pathways to sexual dimorphism in brain structure, personality and cognition. A cohort of 384 individuals were recruited to undergo MRI brain scans, cognitive and personality testing. They also provided blood samples for candidate genotyping in polymorphisms in genes for the androgen receptor, oestrogen receptors, progesterone receptor and aromatase enzyme that converts testosterone to oestrogen. Voxel-based morphometry was used to characterise regional differences in brain volume accounted for by these polymorphisms and the relationship to sex differences in brain volume. Diffusion tensor imaging was then used to determine variation in white matter integrity and structural connectivity due to these polymorphisms. Sex differences in personality and cognition are further investigated in terms of correlations with the polymorphisms and brain structure. Finally an endophenotype approach was used to investigate differential risk for conditions such as Alzheimer’s disease and depression between sexes through related brain and personality-based traits. The neural and molecular genetic mechanisms underlying this risk are inferred from correlations with brain-based measures and genotype. The strengths and weaknesses of this approach and the scientific implications of this work to gender research are discussed.

At this point, anyone who denies biological sex differences in plainly anti-science.
Get over yourself and learn something or GTFO loser

Paper: Methods and Assumptions of Research in Behavioral Genetics

http://web.udl.es/usuaris/e4650869/genialitat.cat/continguts/Methods%20in%20Behavior%20Genetics.pdf

Mendelian is…. outdated. Dominant/recessive doesn’t work on the level of behavioural traits we observe, for the same reason there isn’t a “gene for X” as the papers declare, the interactions alone require a great deal of processing power and the outcomes will become clear over the coming decades.
But the gist in this is good.

Drugs #101: Addiction and Physical Dependence

They’re completely separate things.
A drug is a typically organic substance that can impair physiological functioning or kill when given to the healthy population and a drug as medicine is a chemical composition that will repair your improper bodily functioning or you will die without it in an individual body, long term. Addicts may develop non-medicinal physical dependence but medically-obligated physical dependents are not addicts per se.

A drug user with medical physical dependence only can take a processed form of their medicine without the psychological effects (commonly a high) very happily whereas an addict would require the high, the specific form of drug is merely a trigger for the brain created by past memories of use by the amygdala. These extreme-intensity usage memories create many of the symptoms of withdrawal (psychosomatic) and delude the brain into believing it genuinely needs the drug e.g. claims marijuana is as healthy as a vitamin and the push to normalize (the societal danger of addict populations, social contagion and acceptability).

The sole cause of addiction beyond a doubt is beginning use in the first place. It is impossible to be addicted to (or physically dependent on) a substance the body (and brain) has never experienced. This is a self-selecting type of stupidity (hubris/arrogance) regularly found in teenagers (immature prefrontal cortex) because such users do not think or disbelieve their mind could be compromised by addiction. Their brains already create this illusion to necessitate the anticipated reward (high) prior to initial use or they wouldn’t take it (such as the processed form with no high). The foolproof layman method to test for addiction is simple: substance deprivation for a year. Prepare for a list of excuses.

A physical dependency is often created by doctors to treat patients with chronic conditions, usually chronic pain symptoms (ongoing). Addicts try to ape this category (some sincerely, others deceptively) but are increasingly thwarted by processed (reward-weakened) variants of their poison. Specific advocates for drug legalization ignore the essential fact of escalation and compensation. As part of the brain’s hedonic treadmill, it craves increasingly more of the reward from use, compelling drug users to harder toxins (harder reward, creating deeper addiction and physical damage) and this is the biological component of addiction that makes the habitual behaviour of use so challenging to physically extinguish from the brain.

Physical dependency creates withdrawal symptoms too but the patient’s individual physical needs (inc. not dying) and substance type distinguish this from addicts e.g. insulin to a diabetic.The human brain is connected to facilitate the reward response feedback loops because they are evolutionally guided by the basic needs to survive (food, water, sex) and this is why there is no such thing as a food addict, water addict or sex addict, merely people with impulse control issues seeking a social ‘displacement of responsibility’. Beyond these essential elements for the sustenance of our individual life and species general, anything chemical creating a vacuous boost in the reward system is a drug, whether you like it or not. Drug users resent the stigma for their activities whether or not their poison is legal (ethanol/alcohol, tobacco, marijuana, cocaine etc) because the positive emotional response loop (dopamine, serotonin release) caused by their usage memories creates defensive dissonance when challenged by non-users. Even polite persistent enquiry can sometimes trigger a psychotic episode where the patient is completely detached from reality and VERY DANGEROUS. This is why trained professionals intervene. In the latter stages, the drug/s become integrated into personal identity and extraction or therapeutic measures become unlikely to resolve the issue without constant medical care (rehabilitation facilities). Moreover, this reduces the risk of sudden death caused by the somatic shock of going ‘clean’ and allows overall physiological strength to be built up (reverse what the drugs did) while the problem is gradually resolved.

If a substance exists in a natural form within, say, a foodstuff, it is not addictive because food reward circuits are natural and normal and can never be extinguished. This is why milk (dairy), sugar, chocolate, chilli, coffee and caffeine ‘addiction’ is a misnomer. However, a person habitually needing a purified artificial version of these may constitute a non-medical physical dependence or perhaps a behavioural addiction e.g. alcoholism. Behavioural addictions require holistic (whole life) perspective for diagnosis e.g. someone who works online cannot be an internet addict if those hours online constitute their occupation (add to their success and life) and they can easily disconnect for a while. Behavioural addictions where they do exist are more accurately termed compulsions and relate to personality disorders or obsessions created by unmet needs. Substitution is the norm where one behaviour is broken, another is taken up. Social contagion is a significant factor for poor impulse control. Behavioural or result-based addictions when positive are discounted for lack of stigma nor bodily harm e.g. ‘high’ grades, promotion (power/status boost), painting. However, they can display withdrawal symptoms from endogenous neurotransmittor levels e.g. low serotonin creates acute compulsiveness completing the cycle to repeat a rewarding behaviour and low dopamine creates psychomotor agitation including pacing and fidgeting, also apathy, chosen social isolation and anhedonia (nothing is enjoyable and everything fast becomes boring).

 

By most definitions, Sherlock Holmes is not an addict. However, he qualifies as an addictive personality with a high arousal threshold and high need for cognition.

By most definitions, Sherlock Holmes is not an addict. However, he qualifies as an addictive personality with a high arousal threshold and excessively superhuman high need for cognition.

Related terms: Dosage Response Curve and (innate) Arousal Thresholds causative of addictive personality tendency.

Post inspired by this video, Sherlock Holmes’ withdrawal symptoms

Mark the positive addiction withdrawal symptoms from endogenous behaviour-triggered stimulation.

And yes, you can be addicted to love.