Racial realities, mixed race fertility and Neanderthals

Hope you poured a drink you could prop a spoon in.

I found stuff by accident again.

http://www.academia.edu/542911/Neanderthal-human_hybrids

Neanderthal women couldn’t conceive with humans.

Different species.

It would be interesting to see if there are fertility problems between races…

I thought.
Google autocompletes “are mixed race less fertile”
Interesting.

Rumours that Asians and Africans have more trouble with IVF, even among those who already need IVF.

http://webarchive.nationalarchives.gov.uk/20160105160709/http://www.ons.gov.uk/ons/about-ons/business-transparency/freedom-of-information/what-can-i-request/previous-foi-requests/health-and-social-care/information-regarding-mixed-race-parentage/index.html

Infertility information isn’t gathered, which sounds weird for a data-mining project???
They collect the differing types of data but somehow can’t put them together? I call BS.

http://sociobiologicalmusings.blogspot.co.uk/2011/10/problems-with-mixed-race-marriages-and.html
Cavalli-Sforza’s genetic distances.
I knew HBD would have the answer.

“It is almost the equivalent to having twice the number of children… Thus assortative mating by ethnicity can have large fitness benefits, the largest derived from choosing mates within geographic races.”

they pass on more of themselves, less genetic death per carrier (child)
May increase the values for Ks in parental investment theory.

“In other words and general terms, a white mother will be almost as twice as closely related to a child with a white father versus a child with a black father.”

Bear in mind, this isn’t opinion. It’s genetic.

“But when I turn to the mirror in my bedroom to admire us together, I am shocked. She seems so alien.”
LOL
The non-white always benefits far in excess due to dominating the white phenotypes.
They’re hoping to reduce their mutation load/disease risk. The white party loses.

“But still, I can’t shake off the feeling of unease. I didn’t realise how much her looking different would matter… When she was born, pale but with lots of dark hair, I asked the midwife if her eyes would stay blue. ‘Asian genes are very strong,’ she said in what I took to be an ominous tone. No more Brady Bunch kids for me. The midwife has been proved right and every day my baby’s eyes get a little darker.””

Wow so Nazi to insist your daughter look like you. /s
WTF do these r-types expect?

“Since parents share fewer genes with mixed-race children, people involved in interracial marriages are short-changing their own genes, which might explain why people engaged in mixed-race relationships often tend to have lower mate value.”

oh yeah
they signal how they can’t get one of their own so they settled
we all know how attractive desperation is, socially and sexually

“In general, mixed-race people have more health problems.”
The hybrid vigour thing was always a lie, it’s reduced fitness.
According to the field of medicine.

In other words, an argument could be made that mixed-race families are maladaptive — both for the parents and the children — and undermine one’s genetic interests. As noted by various commenters, multiracial families often do not possess the harmony, cooperation and purposefulness of same-race families, because mixed-race families lack the focus of genetic investment and returns that same-race families possess.”

Like a kind of …selection…

White British genes best at IVF *hums national anthem*

https://www.sciencedaily.com/releases/2016/08/160818212907.htm
“The study also found that some groups of women including South Asian Bangladeshi, Black African, Middle Eastern, have a significantly lower number of eggs collected than White British women.”
weeaboos lament
“Furthermore, the increased prevalence of polycystic ovary syndrome (PCOS) in south Asian women may have an impact on egg quality and lower implantation rates.”
“The data suggests that ethnicity is a major independent factor determining the chances of IVF or ICSI treatment success.”
No shit Sherlock. Could it be something of a biological thing going on here…?
“While the reason for this association is difficult to explain, the potential factors could be the observed differences in cause of infertility, ovarian response, fertilisation rates and implantation rates, which are all independent predictors of IVF success.”
Difficult? Awkward.
“”Infertility affects 10-15% of the population and more people are seeking fertility treatment.”
Isn’t that approaching the rate of mixed race couples? Coincidence, I’m sure. I’d like to check but nobody gives enough of a damn about them to collect the data.
“The reasons behind the variation need to be looked at in more detail but in the future could potentially help improve success rates amongst all groups of women.””
Not if it’s genetic.

Another study!
https://www.sciencedaily.com/releases/2013/10/131029220758.htm
“live birth rates of ethnic women were significantly lower”

White women healthiest post-birth
https://www.sciencedaily.com/releases/2013/02/130211102222.htm
almost like an evolved advantage…

Disgust toward mixed-race couples at biological level
https://phys.org/news/2016-08-bias-disgust-mixed-race-couples.html
“”That indicates that viewing images of interracial couples evokes disgust at a neural level,” Skinner said.”
“Participants were quicker to associate interracial couples with non-human animals and same-race couples with humans.”
lol
do you ‘fucking love science’ now?

Mixed race babies weaker babies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867623/
“contribute to the substantially higher demonstrated risk for stillbirth”
it’s healthy! they tell you
only because they aren’t collecting the data to argue otherwise
I would sue because that’s academic neglect and actual systemic racism.

You really have to search even for data on successful births, then there’s NO fitness advantage by rate.
http://paa2012.princeton.edu/papers/122287
“This paper investigates whether mixed race couples have different or same fertility level than same race couples”
“Same race couples have on average 1.93 children while mixed couples have 2.05 children. Same race couples have lower fertility because the majority of those couples are white. This data shows that homo and heterogamous unions do not have the same fertility level”
“Mixed race couples have fertility levels that fall in between same race couples; not as high as black or brown couples but not as low as the white couple.”
Regression to the mean, my old friend.

Ya gotta really LOOK.
http://www.medpagetoday.com/obgyn/pregnancy/11111
Oh look, mutation load.

https://www.quora.com/Is-it-harder-for-interracial-couples-to-conceive
“I can’t find any studies on this at all.”
Red flag to ANYONE else?
“I heard from student of medicine that interracial couples could have problem conceiving child because of their racial differences.”
Why not study it?
They’re screwing over the mixed-race kids.
Possibly killing them, in the long run. That’s just sick, not to study it. Parents deserve to know.

The manosphere dudes with Yellow Fever won’t be pleased.
http://blogs.discovermagazine.com/gnxp/2008/10/the-prenatal-wages-of-interracial-relationships/
https://www.eurekalert.org/pub_releases/2008-10/sumc-acf092508.php
“In both of these cases there isn’t something mystical going on; God is not smiting those who are sinning by crossing racial lines. Human spontaneous abortion rates are high. Much of this might be due to mother-child immune system responses. It shouldn’t surprise anyone that people from very genetically distinct populations have very different immune profiles. …”
It does if they grow up hearing everyone is biologically equal.
There is some data which might suggest that genetic relatedness increases reproductive fitness, possibly because of reduced risk of immune incompatibilities between mother and fetus when the father is more closely related to the mother. It stands to reason then that as the father becomes more genetically distant the likelihood of incompatibilities might increase. All of this means that genes matter, and they matter in ways we can possibly predict.”

Then predict.

Do the science.

Your JOB.

http://brembs.net/hamilton/
Irony, the name.
K-selected cooperation in a formula.

Inbreeding is generally better than outbreeding due to inclusive fitness.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088844/
applies to other species too
As long as you don’t screw close relations and over many generations, you’re fine.

Wasps! That’s the depth of the barrel I scrape for data on this. Nothing to hide, nothing to fear!
https://academic.oup.com/beheco/article/22/2/337/208104/Reproductive-skew-is-highly-variable-and
Because for some reason nobody takes the data in humans.
Some strange, open-minded reason.
They find cooperation. In insects.

Needs more genetics, more studies. Generally correct.

Link: Nearly all of our medical research is wrong

Nearly all of our medical research is wrong

OT: The vaccine brigade would do well to remember the field has problems…

Don’t expect that cure for cancer soon, the charities should be sued for false advertising.

This is mostly a pharma finding.

Something is rotten in the state of biomedical research. Everyone who works in the field knows this on some level. We applaud presentations by colleagues at conferences, hoping that they will extend the same courtesy to us, but we know in our hearts that the majority or even the vast majority of our research claims are false.

This paper linked: http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124#pmed-0020124-b6

When it came to light that the biotechnology firm Amgen tried to reproduce 53 “landmark” cancer studies and managed to confirm only six, scientists were “shocked.”

Sure they were.

“A lot of what is published is incorrect” ~ The Lancet

Click to access PIIS0140-6736%2815%2960696-1.pdf

“A lot of what is published is incorrect.” I’m not allowed to say who made this remark because we were asked to observe Chatham House rules. We were also asked not to take photographs of slides. Those who worked for government agencies pleaded that their comments especially remain unquoted, since the forthcoming UK election meant they were living in “purdah”— chilling state where severe restrictions on freedom of speech are placed on anyone on the government’s payroll. Why the paranoid concern for secrecy and non-attribution? Because this symposium—on the reproducibility and reliability of biomedical research, held at the Wellcome Trust in London last week—ouched on one of the most sensitive issues in science today: the idea that something has gone fundamentally wrong with one of our greatest human creations…..

Oh, I have stories about Chatham House.

deanwinchester supernatural wink flirty hey hello nice

Britain changes BMI standard to reflect race reality

http://newobserveronline.com/racial-differences-confirmed-once-again-as-britain-sets-new-bmi-standards-for-asians/

The whole thing is good.

The reality of race has been confirmed once again with the news that the UK’s National Institute for Health and Care Excellence (NICE) has changed standard obesity measure threshold for Asians and other “ethnic groups” living in that country.

According to new rules set out by NICE, Asians and “other ethnic groups” (whites, as readers will know, in the eyes of the establishment, are not an “ethnic group”) must be extra careful about their weight because they are prone to diseases like diabetes.

The new target brings the UK in line with Indian and World Health Organization recommendations and says that a 5ft 11in (1.8m) Asian man should weigh below 165 lb (75kg).

According to the official guidance on the NICE website, Professor Mike Kelly, Director of the Centre for Public Health at NICE, said that the “point at which the level of body fat becomes risky to health varies between ethnic groups.

“Healthcare workers should apply lower thresholds to people from black, Asian and other minority ethnic groups than to those of white European descent….

I can hear the chanting now. Biology is racist.

It’s like, but would you rather they die because you dislike the truth?

I think the latter would be more racist, don’t you?

Equal ≠ Same: Sex Differences in the Human Brain

http://dana.org/Cerebrum/2014/Equal_%E2%89%A0_The_Same__Sex_Differences_in_the_Human_Brain/

…The answer to the first question is that the biomedical community has long operated on what is increasingly being viewed as a false assumption: that biological sex matters little, if at all, in most areas of medicine…

Technically, feminism has encouraged doctors to kill people.

I’ll quote the Darwinian part since some pricks people keep getting this finer point wrong confused;

What Darwin Actually Said
We should have expected all along that the brains of men and women are a complex mix of similarities and differences, at least if we believed in evolution as Charles Darwin described it. Darwin did not believe that evolution proceeded by natural selection. In fact, he was completely clear that, in his view, evolution by natural selection alone must fail. He knew that natural selection alone failed to explain far too many phenomena (most famously the male peacock’s tail). What Darwin actually said was that evolution proceeded largely through two distinct mechanisms: natural selection and sexual selection. The former acted on the basis of whether an organism survived; the latter acted on whether it made a baby. In his second book, The Descent of Man, and Selection in Relation to Sex, Darwin developed this idea (first presented in the original edition of The Origin of Species) and made explicit his view that the beneficial effects of sexual selection must at times outweigh the negative effects of natural selection (again, think of the male peacock’s tail)….

I've been waiting ages to use this one, it's so apt to academics

Good rule of thumb: Darwin is always right.

I’ll be posting at least one study on this again today. Probably two.

 

Neanderthals’ DNA legacy linked to modern ailments

Full from http://news.harvard.edu/gazette/story/2014/01/neanderthals-dna-legacy-linked-to-modern-ailments/ ;

Remnants of Neanderthal DNA in modern humans are associated with genes affecting type 2 diabetes, Crohn’s disease, lupus, biliary cirrhosis, and smoking behavior. They also concentrate in genes that influence skin and hair characteristics. At the same time, Neanderthal DNA is conspicuously low in regions of the X chromosome and testes-specific genes.

The research, led by Harvard Medical School (HMS) geneticists and published Jan. 29 in Nature, suggests ways in which genetic material inherited from Neanderthals has proven both adaptive and maladaptive for modern humans. (A related paper by a separate team was published concurrently in Science.)

“Now that we can estimate the probability that a particular genetic variant arose from Neanderthals, we can begin to understand how that inherited DNA affects us,” said David Reich, professor of genetics at HMS and senior author of the paper.

In the past few years, studies by groups including Reich’s have revealed that present-day people of non-African ancestry trace an average of about 2 percent of their genomes to Neanderthals — a legacy of interbreeding between humans and Neanderthals that the team previously showed occurred between 40,000 to 80,000 years ago. (Indigenous Africans have little or no Neanderthal DNA because their ancestors did not breed with Neanderthals, who lived in Europe and Asia.)

Several teams have since been able to flag Neanderthal DNA at certain locations in the non-African human genome, but until now, there was no survey of Neanderthal ancestry across the genome and little understanding of the biological significance of that genetic heritage.

“The story of early human evolution is captivating in itself, yet it also has far-reaching implications for understanding the organization of the modern human genome,” said Irene A. Eckstrand of the National Institutes of Health’s National Institute of General Medical Sciences, which partially funded the research. “Every piece of this story that we uncover tells us more about our ancestors’ genetic contributions to modern human health and disease.”

Deserts and oases

Reich and his colleagues — including Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology in Germany — analyzed genetic variants in 846 people of non-African heritage, 176 people from sub-Saharan Africa, and a 50,000-year-old Neanderthal whose high-quality genome sequence the team published in 2013.

The most powerful information the researchers used to determine whether a gene variant came from a Neanderthal was if it appeared in some non-Africans and the Neanderthal, but not in the sub-Saharan Africans.

Using this and other types of information, the team found that some areas of the modern non-African human genome were rich in Neanderthal DNA, which may have been helpful for human survival, while other areas were more like “deserts” with far less Neanderthal ancestry than average.

The barren areas were the “most exciting” finding, said first author Sriram Sankararaman of HMS and the Broad Institute of Harvard and MIT. “It suggests the introduction of some of these Neanderthal mutations was harmful to the ancestors of non-Africans and that these mutations were later removed by the action of natural selection.”

The team showed that the areas with reduced Neanderthal ancestry tend to cluster in two parts of our genomes: genes that are most active in the male germline (the testes) and genes on the X chromosome. This pattern has been linked in many animals to a phenomenon known as hybrid infertility, where the offspring of a male from one subspecies and a female from another have low or no fertility.

“This suggests that when ancient humans met and mixed with Neanderthals, the two species were at the edge of biological incompatibility,” said Reich, who is also a senior associate member of the Broad Institute and an investigator at the Howard Hughes Medical Institute. Present-day human populations, which can be separated from one another by as much as 100,000 years (such as West Africans and Europeans), are fully compatible with no evidence of increased male infertility. In contrast, ancient human and Neanderthal populations apparently faced interbreeding challenges after 500,000 years of evolutionary separation.

“It is fascinating that these types of problems could arise over that short a time scale,” Reich said.

A lasting heritage

The team also measured how Neanderthal DNA present in human genomes today affects keratin production and disease risk.

Neanderthal ancestry is increased in genes affecting keratin filaments. This fibrous protein lends toughness to skin, hair, and nails and can be beneficial in colder environments by providing thicker insulation, said Reich. “It’s tempting to think that Neanderthals were already adapted to the non-African environment and provided this genetic benefit to humans,” he speculated.

The researchers also showed that nine previously identified human genetic variants known to be associated with specific traits likely came from Neanderthals. These variants affect diseases related to immune function and also some behaviors, such as the ability to stop smoking. The team expects that more variants will be found to have Neanderthal origins.

The team has already begun trying to improve their human genome ancestry results by analyzing multiple Neanderthals instead of one. Together with colleagues in Britain, they have developed a test that can detect most of the approximately 100,000 mutations of Neanderthal origin they discovered in people of European ancestry; they are conducting an analysis in a biobank containing genetic data from half a million Britons.

I VOLUNTEER.

“I expect that this study will result in a better and more systematic understanding of how Neanderthal ancestry affects variation in human traits today,” said Sankararaman.

As another next step, the team is studying genome sequences from people from Papua New Guinea to build a database of genetic variants that can be compared to those of Denisovans, a third population of ancient humans that left most of its genetic traces in Oceania but little in mainland Eurasia.

How did I find this story? Funny story.
A moron on tumblr who doesn’t understand evolution. For lolz;

SJWsdon'tdoDarwinwtfhowfacepalmingsrsly
No one told them Neanderthals had high IQs and ginger hair. Hush. Don’t spoil it for them.
Let them drone on about discredited Afrocentrist ‘racial purity’ pipedreams. And evolution is a constant process for the record. “We are changing the main narrative. Neanderthals were just as adaptable and in many ways, simply victims of their own success.” How’s Africa doing on the global scale compared to every other country? Still rape and murder capital of the world? Hmm.

Paper: Molecular Sex Differences in Human Serum (Asperger’s application)

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0051504

Sex-specific molecular differences were detected in serum of typical controls and these were reproducible across independent cohorts. This study extends current knowledge of sex differences in biological functions involved in metabolism and immune function. Deviations from typical sex differences were found in a cluster of molecules in Asperger syndrome. These findings illustrate the importance of investigating the influence of sex on medical conditions.

What a shame the new DSM removes Asperger’s as a seperate form of autism. Still. It goes to show how strong inter-sexual differences are medically. This is important stuff.

Trans Slate says sexing a baby for records at birth is abuse

http://www.slate.com/blogs/outward/2014/06/26/infant_gender_assignment_unnecessary_and_potentially_harmful.html

Literally looking and say what is there. They try to make it scary by calling it infant gender assignment. Biological sex isn’t gender. Sex isn’t assigned, you have never been anything else since you existed. Can’t scalpel away every cell in your body.

The metaphor they use can hilariously also be applied to vaccination (peer pressure, side effects)

It ends with:

“Is it better to play the odds, or play it safe? Think carefully. Infant gender assignment might just be Russian roulette with your baby’s life.”

Fearmongering? What fearmongering? There’s no personal agenda here?

I can tell this won’t happen because it interferes with Gov’s desire to acquire personal medical information.
Still fucking annoying though. These people need to be stopped from controlling the lives of others, especially real vulnerable groups like children. It interferes directly with the medical profession on the basis of personal minority belief (but Christianity is meant to be evil) and their ability to do their job. Including save lives.

Imagine the implication. If a child is suffering from a sex-specific ailment, the doctor cannot acknowledge it to treat it. These crazy trans groups enforcing their beliefs on the rest of us will directly cause deaths if they are given their way.

Troublesome Inheritance Review: Different races exist. So what?

http://reason.com/archives/2014/06/20/different-races-exist-so-what

Please, continue that train of thought.

Please, continue that train of thought.

It’s almost as if it’s getting through… Almost.

This has huge implications for medicine, which go unmentioned.

I love how poor critics think saying they don’t like an idea is equivalent to refuting it, especially when they have nothing which explains the same evidence. This is why they’re critics and not creators.

How clean is your pap smear? That metal speculum?

http://medidex.com/medical-devices/99-issues-relating-to-disposable-and-reusable-vaginal-specula.html

I was tipped off about this and I’m mortified as a woman.

“SMTL carried out a survey of mainly GP practices with regard to their use of disposable and reusable vaginal specula. Disturbing reprocessing practices were revealed in some surgeries, including some practices completely ignoring MDA advice. Most users performing in-house reprocessing were not complying with best practice as recommended by the Department of Health through their various device bulletins and HTM documents.

Many GP practices could reduce the level of risk by investing in better reprocessing systems, contracting out their reprocessing completely, or through the use of disposable specula. Practices may also be able to reduce their costs by using disposable specula or by contracting out their reprocessing.”

Imagine the lawsuits. The NHS has been pushing ALL women above a fixed age to have this exam.

“There is little in the literature relating to the issues surrounding reusable vaginal specula.”

Perhaps this is partially behind the soaring HPV rates?

“They concluded that HPV infected cells can be found on instruments inserted into the vagina of women with HPV infection, and that if these instruments are not cleaned and sterilized properly, they will be a potential source of infection for subsequent patients.”

HPV can cause cancer, btw.

“correct pasteurisation (immersion in water at 80 C for 5 minutes) would inactivate papillomaviruses, herpes viruses, and HIV.

That isn’t the same as clean. Are women told this? I’ve never heard of it. Uninformed consent. Bleeding is a “common” side effect of these exams, hence the HIV bolded.

“Although there is little in the literature regarding cross-infection from inadequately sterilized specula, we live in an increasingly litigious society. One strand in the defence against patient claims of cross infection from poorly decontaminated and sterilized instruments would be complete documentation of the process, including logbooks, written operating procedures, training records, test results and maintenance data. The other possibility is to use pre-sterilized disposable CE marked equipment from a reputable manufacturer. Either would make it more difficult for a patient to mount a successful legal claim.”

Oh, they don’t really care about patients at all, they want the NHS to avoid the mass of lawsuits.

Here’s Feminist Midwife explaining the infectious problems with these supposedly ‘safe’ exams, I wish feminism would complain about important problems like this (guys, you’re sticking your dick in this too, it matters, and you might think a woman’s cheating when she isn’t).

http://www.feministmidwife.com/2013/03/12/very-clean-pap-smears/

Apparently, even the disposable ones can be contaminated by the awkward, common habit of touching lots of things with gloved hands and then the speculum, when it’s clean out of the container. (We must assume it’s clean out of the container or I’m out. Yet checking manufacturing/personnel would be vital).

Can someone look into probes for me? I can only find information like this: “High-Level Disinfection destroys all microorganisms except some endospores” ~ forum source

And forceps are a problem too. Contamination news story in Canada Don’t these devices have hinges? Springs? Things that gather dirt and grime and cannot, in most cases, be taken apart for cleaning?

IV fluid too?? FFS!

Study on HPV infection from non-sexual means at the clinic e.g. gloved hands!
And HPV is in semen.
“The incidence of anal cancer among homosexual men exceeds that of cervical cancer in unscreened women.”
I’m going to stop looking now, it’s too disgusting.

UPDATE

Further information

http://jid.oxfordjournals.org/content/176/4/1076.full.pdf “The data suggest that further study of nonsexual spread of high-risk genital HPV via fomites is warranted.”

http://www.cancer.org/acs/groups/cid/documents/webcontent/003167-pdf.pdf “A woman with multiple sexual partners should use condoms to lower her risk of sexually transmitted infections no matter what other form of contraception she uses.” Rather defeats the purpose of the Pill, doesn’t it? “Certain types of sexual behavior increase a woman’s risk of getting HPV infection, such as having sex at an early age and having many sex partners.” Why don’t men get the vaccine when they’re passing it on?

Update: it gets worse, the lubes used by doctors are probably bad for us too.

Should you be worried about your vagina absorbing the ingredients in your lube?