Aluminium kinetics in the brain

Vaccine Aluminum Travels Into The Brain

Parents can be reassured that the trace quantities of aluminum in vaccines can’t possibly do harm.
-Dr Paul Offit: Vaccine promoter, vaccine patent licensor, and autism pundit, 2015

…the existing evidence on the toxicology and pharmacokinetics of Al adjuvants…altogether strongly implicate these compounds as contributors to the rising prevalence of neurobehavioural disorders in children.
-Dr Chris Shaw, Neuroscientist and aluminum researcher at University of British Columbia, 2013.

But it was assumed that the AANs dissolve rapidly in body fluids, and the resulting Al3+ is eliminated in urine, just like ingested aluminum. However, this simple model is wrong.

assumed by who?

Any asshole can assume, that isn’t science.

Vaccine promoters assume that Al adjuvant is safely eliminated by dissolution and urinary excretion. Thats why vaccine promoters believe only the blood concentration of Al3+ is important. We now know this is wrong. The Al adjuvant dissolves very slowly and so can remain in the body for many months or years. Also, its not just the dissolved Al3+ thats toxic; the Al adjuvant particles are also toxic. 

If you wanted to fuck up little white boys, brain damage is a primary candidate.

Cripple their best resource, right?

The above model is wrong. What actually happens is a type of immune cell called a macrophage (MF) ingests (called “phagocytosis”) the AANs. Eating foreign material is a primary function of MFs. When MFs detect bacteria or debris, the MFs eat it, and destroy it with enzymes.

The problem is that AANs are not digested by the MF enzymes. Consequently, the AANs remain inside the MFs for a long time. The AANs can persist for years. MFs that consume the AANs become highly contaminated with aluminum, and spread the aluminum wherever they go. And they go everywhere in the body.

Sounds like a chemical weapon.

The MFs travel across the blood brain barrier (BBB) when there is inflammation in the brain. The MFs, once loaded with AANs, act like a Trojan Horse and carry the AANs into the brain. This is harmful, because the brain is very sensitive to aluminum.

Below is a diagram illustrating how AANs travel around the body and into the brain.

Shame parents for not injecting the child with poison, because peer pressure to conform is more important than ‘first harm none’.

Herd immunity’s a myth anyway, even 100% coverage (impossible) wouldn’t work. Covered previously.

Nerve damage in white males

Coincidental, just don’t look around.

https://www.sciencedirect.com/science/article/abs/pii/S0940299399800724

“The aim of this study was to investigate the effects of squalene on the central and peripheral nervous systems in rat at the ultrastructural level. Squalene was administered at a dose of 20 g/kg body weight, once daily for 4 days, and the animals were sacrificed 7 days and 30 days after the initiation of the experiment. After 7 days a mild swelling of mitochondria and dilation of the Golgi complex cisterns in few neurons in the cerebral cortex and hippocampus were observed. The swelling of astrocytes and their processes was also seen. Some myelin sheaths in the cerebral white matter were disintegrated. In the peripheral nervous system (the sciatic nerve), a damage of the Schwann cells, a destruction of the myelin sheaths, and lipid-like deposits between myelin lamellae causing a secondary compression of axons were present.”

Mercury also destroys myelin sheaths. However, it is eventually cleared from the body by chelating factors in the diet, with the exception of repeat doses e.g. from amalgam.
Why are modern boys slow in school, weirdly dulled and heavy addicts of social media, porn etc.?

Squalene administration caused a stimulation of fibroblast to synthesize collagen and an activation of macrophages in the perineurium.”

The collagen bit makes it fine topically for vain women (including moi).

“After 30 days, the lipid-like material was present in some neurons as well as in the myelin sheaths in the central nervous system. Endothelial cells were hypertrophic and a few demonstrated features of apoptosis.”

I find it odd a famous billionaire magically had a son who “grew out of” autism…

Italians supposedly tested a vaccine in December and found it …didn’t contain a vaccine. At all.
So technically, the things labelled and given as ‘vaccines’ cause issues.

What’s being called vaccinegate is this mystery mix death potion sold and forced on children as “vaccines”.

“Vaccinegate: Initial results on Infanrix Hexa chemical composition”
http://data.over-blog-kiwi.com/1/47/73/60/20190101/ob_d9ff7d_corelva-rapport-composition-vaccin-in.pdf

Almost like genetic targeting, but you’d need enough dumb ones submitting free samples for “research” in the T&Cs to make that a bioweapon.
You’d also need to own the labs and pharmaceutical companies. Do they use squalene?
https://www.cdc.gov/flu/protect/vaccine/adjuvant.htm See end.
Male genes are easier to target than female but the rumour is that the three-part tetanus (no such thing, it’s one-shot) is intended to prevent pregnancy.

In Infanrix Hexa we found
● chemical contamination from the manufacturing process or cross-contamination with other manufacturing lines;
● chemical toxins;
● bacterial peptide toxins;
● insoluble and indigestible macromolecule that reacts to the protein assay, but cannot be recognized by any protein databases.

We have not found:
● Protein antigens of diphtheria toxoids, tetanus, pertussis, hepatitis B, haemophylus influenzae B, Poliomyelitis 1-2-3;
● Formaldehyde and glutaraldehyde, phenoxyethanol, antibiotic residues indicated in the composition;

Autism symptoms is not autism, polio symptoms is not polio.

Note the wording.

https://www.iflscience.com/health-and-medicine/us-outbreak-paralysis-may-have-been-caused-newly-identified-virus/

“May”

I may be George Soros in a wig. Long odds but…. maybe.

Would there happen to be perineurium damage?

https://www.nbcnews.com/health/health-news/cdc-still-stumped-cause-mystery-paralysis-kids-n750276

I fucking bet they are. Bet you squalene antibodies in their bloodstream, easily resolved with another injection for the immune system to attack said antibodies.

They won’t pay out the Social Security bennies.

CDC:

FLUAD is a standard-dose, three-component (trivalent) inactivated flu vaccine, manufactured by Seqirus that contains an adjuvant. FLUAD is designed specifically for people 65 years and older.

Uhuh. Which adjuvant is this?

MF59 is an oil-in-water emulsion of squalene oil. Squalene, a naturally occurring substance found in humans, animals and plants, is highly purified for the vaccine manufacturing process. FLUAD is approved for use among people 65 years and older, who often have a lower protective immune response after flu vaccination compared to younger, healthier people.

I hate being right.

I hate it, I hate it, I hate it.

Modest drinking health claim debunked

https://www.reuters.com/article/us-health-alcohol-stroke-idUSKCN1RG2ZI
Well, duh.

Blood pressure and stroke risk rise steadily the more alcohol people drink, and previous claims that one or two drinks a day might protect against stroke are not true, according to the results of a major genetic study.”

Drinks companies lied to us?

The research, which used data from a 160,000-strong cohort of Chinese adults, many of whom are unable to drink alcohol due to genetic intolerance, found that people who drink moderately – consuming 10 to 20 grams of alcohol a day – raise their risk of stroke by 10 to 15 percent.

It isn’t good for anyone, America won’t take the data. It’s addicted, Prohibition was required to make it seem glamorous.
Alcohol affects your DNA but the conspiracy people won’t touch it with a barge pole.
Yet Millennials are shamed for not going into debt poisoning themselves.
Why do men die younger, again?

For heavy drinkers, consuming four or more drinks a day, blood pressure rises significantly and the risk of stroke increases by around 35 percent, the study found.

Drinks = units.

“The key message here is that, at least for stroke, there is no protective effect of moderate drinking,” said Zhengming Chen, a professor at Oxford University’s Nuffield Department of Population Health who co-led the research. “The genetic evidence shows the protective effect is not real.”

Fuck, genetics? How dare you hint at racial differences.

I couldn’t make it up

The wages of sin are death.

https://www.theguardian.com/society/2018/jun/21/alzheimers-link-to-herpes-virus-in-brain-say-scientists

“Free love”

How’s that sexual revolution?

Still doubling down huh?

Yeah, your parents couldn’t have a point, they were just squares.

I don’t think it is the herpes, although that damage is real.

I think it’s the aluminium still.

HPV in the brain

Yes, in.

http://www.miriamgrossmanmd.com/say-its-not-so-hpv-in-the-brain/

“We know that HPV can cross the placenta and infect the fetus. In one study, this happened in over twelve per cent of women with HPV.”

As always it’s the innocent who suffer.
The sins of the father…

https://www.biblegateway.com/passage/?search=Exodus+34%3A7&version=ESV

“keeping steadfast love for thousands,[a] forgiving iniquity and transgression and sin, but who will by no means clear the guilty, visiting the iniquity of the fathers on the children and the children’s children, to the third and the fourth generation.”

And before you think I’m man-hating, no.

It’s the data.

https://www.sciencenews.org/article/half-adult-males-carry-hpv
“The virus notorious for causing cervical cancer in women also turns up frequently in men and can hang on unnoticed for months or even years, researchers report online March 1 in Lancet. The study solidifies earlier research indicating that human papillomavirus is highly prevalent in men and strengthens the case for vaccinating men and boys against it, the report’s authors say.”

Imagine my shock.

“The study, in the Annals of Internal Medicine, found that 11 million men and 3.2 million women in the United States had oral HPV infections. Among them, 7 million men and 1.4 million women had strains that can cause cancers of the throat, tongue and other areas of the head and neck.”
“The rate was higher among men who also had genital HPV. (Almost half of men aged 18 to 60 have a genital HPV infection, according to the Centers for Disease Control and Prevention.)”

TLDR?

It’s a male-carried disease.
By far (that was a 5:1 male to female ratio, deny it).

7/1.4=5 for the illiterates at home.

https://www.cdc.gov/std/hpv/stdfact-hpv-and-men.htm
The penile cancer risk for men goes unmentioned. Some informed consent, right? Feel empowered yet?
No, there is currently no approved test for HPV in men.”
Routine testing (also called ‘screening’) to check for HPV or HPV-related disease before there are signs or symptom, is not recommended by the CDC”
They want the men to spread it.

Back to the original doctor.

This is major news, and I’m wondering – why no headlines about it? There were no press conferences with Dr Crino, and no statements from SIECUS or Planned Parenthood, our leaders in “comprehensive” sexuality education.

$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$

There’s a double standard at work: if research suggested that sugary drinks cause fetal malformations, it surely would be announced with alarm by every media outlet.

Cover-up isn’t a double standard but okay.

With sexual health it’s always been different. The negative consequences of sexual license are often ignored or minimized. Young people are led to believe that with condoms and STI testing they’re safe, or safe enough. But it’s not so.

“Free lust” is anything but free of consequences. If only the Bible mentioned fornication and how sinning against oneself is different.

I believe that one day there will be congressional hearings about the persistent whitewashing of STIs, the exaggerated efficacy of condoms, and the endorsement by sex educators of high risk behaviors. Until then, the madness continues.”

One day there might be real science, we can all dream!

They make so much money off pelvic exams, which by the way, were pioneered in Nazi concentration camps!

And that’s just the tip of the hooker berg.
It was the same with syphilis and other diseases. Men would catch it, usually from hookers and infect their wife (or eventual wife) and their children would have medical issues (look up the syphilis skulls). Deliberate honeypots for this purpose would bring down an entire nation quickly via its leaders. Wouldn’t it, France?

We have DNA testing to trace precise strains of types but that’s small comfort.

If you can get it from a handshake or a peck on the cheek (children, Europeans) nobody is safe.

The Aluminium Age and Alzheimer’s

Where’s the science?

https://link.springer.com/chapter/10.1007/0-387-23226-5_11
https://www.sciencedirect.com/science/article/pii/S0162013409001731
https://www.sciencedirect.com/science/article/pii/S1878535215001914

“The results demonstrated that Al(III) induced the transformation of the initial random coil structure to the β-sheet configuration in the Aβ40 peptides. These structural changes facilitated the aggregation of Aβ40.”

Meanwhile, denial train. Choo choo!

https://www.alzheimers.org.uk/about-dementia/risk-factors-and-prevention/metals-and-dementia
“Here’s the evidence behind the presence of metals such as copper, zinc, iron and aluminium.”
The first three are needed by the body and not neurotoxins.
“But the evidence doesn’t yet show whether this relationship actually causes Alzheimer’s disease.”
Have you tried checking?
“It is also unclear whether reducing metals in the brain via drugs or reducing our exposure would have any effect.”
It is unclear whether Caesar was stabbed but there is a lot of blood and all these knives might’ve had some effect.
“These metals are essential to the healthy function of our brain,”
100% LIE.
Aluminium is not necessary for any bodily function.
But it makes food manufacturing dirt cheap!


“The body is able to tolerate these metals in small amounts by clearing through the kidneys. ”

Well, clearly not.

These include aluminium and lead, for example it has been shown that if they are not taken out by the kidneys through organ failure or by exposure to extremely high doses these metals are able to deposit in the brain.
These metals are known to cause negative effects in the brain and have been implicated in several neurological conditions.”
Safe as lead, guys!
And no that’s outdated, the body doesn’t really clear it. See end.
“In 1965, researchers found that rabbits injected with an extremely high dose of aluminium developed toxic tau tangles in their brains. This led to speculation that aluminium from cans, cookware, processed foods and even the water supply could be causing dementia.”
But the can manufacturers were slipped a bribe because they recently had to switch from toxic tin.
That generation’s children now seem to be presenting with unprecedented Alzheimer’s…. coincidence?
“Importantly, these results were only seen with extremely high exposures that far exceed the levels that can enter the body through food or potentially through contact with aluminium cookware.”
That limit does not exist and assumes perfect health – no alcoholism, polluted air, toxic water, stress, chronic diseases.
“As yet no study or group of studies has been able to confirm that aluminium is involved in the development of Alzheimer’s disease.”
Ethics and finding the funding.
Also a half-lie, there are many studies. As you’ll see.
“Aluminium is seen in the normal, healthy brain.”

…..No?

No, it isn’t.
Not ever. Not at all.
It shouldn’t get past the barrier.
Normal for the modern world is not healthy.

Opening line here: “Aluminium is neurotoxic.”
https://www.ncbi.nlm.nih.gov/pubmed/24779346

Back to the liars:

“Although aluminium has been seen in amyloid plaques there is no solid evidence that aluminium is increased in the brains of people with Alzheimer’s disease.”
Yes there was, you’re ignoring it.

They dissected Alzheimer’s patients and found it in there.
Blatant lie.

No convincing relationship between amount of exposure or aluminium in the body and the development of Alzheimer’s disease has been established.”
Wait before it didn’t exist and in the very next sentence, it isn’t convincing?
“Aluminium in food and drink is in a form that is not easily absorbed in to the body. Hence the amount taken up is less than 1% of the amount present in food and drink.”
Bullshit. It’s the most processed form it goes through the whole digestive tract and then into the bloodstream like food nutrients.
Less than 1% – per meal or drink. PER meal or drink.
Comforting?
“Most of the aluminium taken into the body is cleaned out by the kidneys.”
Outdated.
And wouldn’t it be the liver?
“failed to find a convincing causal association between aluminium exposure in humans and Alzheimer’s disease.”
Give us the data instead of finding excuses to hide it.
1991, before the cash cow was in full milking rotation
https://www.researchgate.net/publication/21345082_Aluminium_amyloid_and_Alzheimer’s_disease
“exposure to aluminium has been implicated by epidemiological studies and the finding of aluminium in the cerebral plaques and tangles.”
3 decades later? Still covering it up?
While they blame copper:
https://www.keele.ac.uk/research/researchnews/2012/metalsandtheamyloidcascadehypothesisofalzheimersdisease.php
It’s neuroprotective.
“a high brain tissue ratio of copper to aluminium protects against neurotoxicity associated with the deposition of amyloid-b and the amyloid cascade hypothesis.”
“The study on 60 aged human brains identified a number of relationships between the degree of severity of amyloid-b neuropathology and the metal content of tissue from the donor brains. The latter was recently published for aluminium, copper and iron (House et al. (2012) Metallomics 4, 56-65).


Relationships, PLURAL and severity.

“Specifically, the extent and severity of amyloid-b deposition was inversely related to the copper content of brain tissue. Lower copper resulted in more severe and more extensive deposition of amyloid-b in the donor brain.”
But obviously you’re crazy to read about it.
“The research suggested that for those individuals with moderate to severe amyloid pathology, a copper to aluminium ratio of less than 20 predicted dementia.”
“Professor Exley said: “The hypothesis requires further testing but if proven correct it could explain why some individuals with senile plaques do not suffer from dementia. The implication being that a high brain tissue ratio of copper to aluminium protects against neurotoxicity associated with the deposition of amyloid-b and the amyloid cascade hypothesis.””

https://www.sciencedirect.com/science/article/pii/S0162013411002145
Aluminium-specific chelators reduce symptoms. Coincidence?
https://www.sciencedirect.com/science/article/pii/S0161813X1530036X
Effect is seen with low levels too:
https://www.sciencedirect.com/science/article/pii/S0161813X1530036X
By this means, the body burden of aluminum in humans has increased. Epidemiological and experimental findings indicate that aluminum is not as harmless as was previously thought, and that aluminum may contribute to the inception and advancement of Alzheimer’s disease. Epidemiological data is reinforced by indications that aluminum exposure can result in excess inflammatory activity within the brain.


“Evidence is presented that reinforces the likelihood that aluminum is a factor speeding the rate of brain aging. Such acceleration would inevitably enlarge the incidence of age-related neurological diseases.”

Maybe most Baby Boomers would be okay if their brains weren’t poisoned?

https://www.sciencedirect.com/science/article/pii/S0301008210000936
“However, disruption of these mechanisms, or absorption of detrimental metals with no known biological function, alter the ionic balance and can result in a disease state, including several neurodegenerative disorders such as Alzheimer’s disease. Understanding the complex structural and functional interactions of metal ions with the various intracellular and extracellular components of the central nervous system, under normal conditions and during neurodegeneration, is essential for the development of effective therapies.”

I hope you plan on someone in Big Pharma coming to kill you for developing therapies.

https://www.sciencedirect.com/science/article/pii/B9780444508119500471
http://orthomolecular.org/library/jom/2000/articles/2000-v15n01-p021.shtml
Opening line: “Aluminum has been identified as a neurotoxin for over 100 years.”
As safe as lead or mercury.

http://www.alz-disease.org/downloads/Aluminum2.pdf
You know where the society said no studies?
“A 2008 systematic review of studies that included aluminum exposure through drinking water, diet, and occupation found 23 studies demonstrated an increased risk for Alzheimer’s disease with elevated aluminum exposure, 3 found that there was no connection…”
Cover-up? Where’s the science?

I can’t seem to find it, guys!

https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-016-0342-y
We screened 4784 studies and included 60 in the review. Risk factors were considered in six categories: air quality, toxic heavy metals, other metals, other trace elements, occupational-related exposures, and miscellaneous environmental factors. Few studies took a life course approach. There is at least moderate evidence implicating the following risk factors: air pollution; aluminium; silicon; selenium; pesticides; vitamin D deficiency; and electric and magnetic fields.”
Life course is ideal.

https://www.aerzteblatt.de/int/archive/article/193516
There is a threshold.
“Our article examines the question of whether environmental and therapeutic aluminum exposure increases the risk of disease. To this end, Alzheimer’s disease and breast cancer are taken as critical endpoints. Aluminum’s neurotoxic effects in humans and its embryotoxic effects in animal models have been proven (4).”

https://www.futsci.com/uploads/project/file/f004582d987d2142ba418d26149d258d64e024e9.pdf
“An inevitable consequence of humans living in
the Aluminium Age is the presence of aluminium in the
brain. This non-essential, neurotoxic metal gains entry to
the brain throughout all stages of human development,
from the foetus through to old age. Human exposure to
myriad forms of this ubiquitous and omnipresent metal
makes its presence in the brain inevitable, while the
structure and physiology of the brain makes it particularly
susceptible to the accumulation of aluminium with age. In
spite of aluminium’s complete lack of biological essentiality,
it actually participates avidly in brain biochemistry
and substitutes for essential metals in critical biochemical
processes. The degree to which such substitutions are disruptive
and are manifested as biological effects will depend
upon the biological availability of aluminium in any particular
physical or chemical compartment, and will under
all circumstances be exerting an energy load on the brain.
In short, the brain must expend energy in its ‘unconscious’
response to an exposure to biologically available aluminium.
There are many examples where ‘biological effect’
has resulted in aluminium-induced neurotoxicity and most
potently in conditions that have resulted in an aluminiumassociated
encephalopathy. However, since aluminium is
non-essential and not required by the brain, its biological
availability will only rarely achieve such levels of acuity,
and it is more pertinent to consider and investigate the
brain’s response to much lower though sustained levels of
biologically reactive aluminium. This is the level of
exposure that defines the putative role of aluminium in
chronic neurodegenerative disease and, though thoroughly
investigated in numerous animal models, the chronic toxicity
of aluminium has yet to be addressed experimentally
in humans. A feasible test of the ‘aluminium hypothesis’,
whereby aluminium in the human brain is implicated in
chronic neurodegenerative disease, would be to reduce the
brain’s aluminium load to the lowest possible level by noninvasive
means. The simplest way that this aim can be
fulfilled in a significant and relevant population is by
facilitating the urinary excretion of aluminium through the
regular drinking of a silicic acid-rich mineral water over an
extended time period. This will lower the body and
brain burden of aluminium, and by doing so will test
whether brain aluminium contributes significantly to
chronic neurodegenerative diseases such as Alzheimer’s
and Parkinson’s.”

Of course, A Drink is cheaper than all the care of the sick patients and you can’t steal their house legally by telling the council they lack competence.

“Certainly aluminium either directly as a
particulate or indirectly following the dissolution of
nanoparticulates could induce an inflammatory action in
the human brain, and this has been demonstrated in animal
models [64]. The immunopotency of aluminiumbased
adjuvants outside their role as adjuvants in vaccine
and allergy therapies seems to have been largely ignored
as a potential mechanism of aluminium toxicity
throughout the body [65] and especially in the nervous
system [66]. The consistent observation of significant
accumulations of aluminium in the brain should at least
be a warning of the potential for such to participate in
neuroinflammatory toxicity.”

You’d think.

The brain is an obvious target for aluminium toxicity.
Neurotoxicity is evident under acute conditions such as
encephalopathies, and it is predicted but not necessarily
recognised as such under chronic or everyday exposures to
environmental aluminium. The mechanisms of neurotoxicity
are potentially myriad, while their manifestations as
biochemical changes are probably quite subtle for all but
the most vulnerable groups.”

Headaches, stomach aches, etc. “Brain fog” might be entirely toxin based.

“While the latter must include
the foetus and neonate, there are few indications as to the
identities of others who are susceptible to the neurotoxicity
of aluminium. Since the advent of the Hall-He´roult process
(and thereafter Bayer process) towards the end of the
nineteenth century and our ability to extract aluminium
from its inert ores on an industrial scale, we have all been
living in the Aluminium Age [67]. Now, in the twenty-first
century, we can no longer completely avoid environmental
exposure to aluminium. Since there is as yet no proven
requirement for aluminium in any living organism, never
mind in humans, it would be prudent to reduce our
everyday exposure to avoid aluminium entering the body
and persisting in the human brain [68].”

It’s used to process junk food, watch How It’s Made.
When people feel better after giving up junk, it might be aluminium exposure reduction.

It would be easy to study: people who eat a lot of junk and people who don’t, Al urine amounts.

“We have begun to
show that this can be achieved by using nature’s own way
of avoiding biologically available aluminium. We have
shown that regular consumption of silicon-rich mineral
waters both reduce our gastrointestinal uptake of aluminium
and, importantly, facilitate our urinary excretion of
systemic aluminium [48]. Life on Earth evolved in spite of
a crust of aluminosilicate [1]. However, the Hall-He´roult
process and the subsequent arrival of an Aluminium Age
have let the aluminium genie out of the bottle. Our final
wish should be that the unique inorganic chemistry of
aluminium and silicic acid will help to put the genie back
where it can be used effectively but, most importantly,
safely.”

Trans. We evolved to take silicon into our brain but aluminium is taking its place.
It lied on its CV, it needs to be fired.

http://www.academia.edu/12143618/Aluminium_and_Alzheimer_s_Disease_A_Suspicious_Link
“This article summarizes the various ways in which Al induces oxidative stress, eventually leading to cell death. It also gives a brief account of manifold epidemiological studies that relate the abundant occurrence of Al in soil and water and the prevalence of AD. Al carriers, their role in AD, Al in neurofibrillary tangles, biochemical reactions altered by Al influx in mitochondria have been briefly discussed.”
One of the key words is apoptosis…

https://lib.dr.iastate.edu/cgi/viewcontent.cgi?referer=https://www.bing.com/&httpsredir=1&article=11467&context=rtd
https://www.researchgate.net/publication/21666142_Aluminium_accumulation_beta-amyloid_deposition_and_neurofibrillary_changes_in_the_central_nervous_system
“If aluminium contributes to the development of sporadic AD, it must do so indirectly, perhaps via effects on the synthesis or metabolism of APP, or by contributing generally to the age-related attrition of neurons and thus reducing the threshold for deficits produced by more specific disease-related processes.”

Final study describes a mechanism.

https://core.ac.uk/download/pdf/81923975.pdf
Back-up PDFs are always useful.

https://www.tandfonline.com/doi/abs/10.3109/07853898909149192?journalCode=iann20

https://www.deepdyve.com/lp/elsevier/demonstration-of-aluminum-in-amyloid-fibers-in-the-cores-of-senile-cwa8nRkSAh

https://febs.onlinelibrary.wiley.com/doi/full/10.1016/j.febslet.2006.10.075
Active effect of aluminium on the brain’s self-cleaning.

https://www.frontiersin.org/articles/10.3389/fneur.2014.00167/full
“Aluminum, as an extremely high charge density cation (Z2/r = 18), has the remarkable capability to both (1) aggregate and compact Aβ42 peptide monomers into higher order, more neurotoxic oligomeric, and fibrillar structures, and (2) impair, at the molecular-genetic* level, the cellular machinery responsible for Aβ42 peptide monomer phagocytosis and clearance from the cell (4–13).”

*Hints at genetic damage.

Apparently the levels we ingest are “physiologically realistic.” As in, it can affect you.

They need chelation therapy.