Study: Placebo often has same effect as ‘real’ treatment

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062599

Placebos and treatments often have similar effect sizes. Placebos with comparatively powerful effects can benefit patients either alone or as part of a therapeutic regime, and trials involving such placebos must be adequately blinded.

Might wanna call up the homeopaths, at least water is cheaper to produce.

We all have those days, months.... YEARS.

I demand biology for proof of your mental illness. BP shifts would be sufficient, damn, anything to distinguish you from a method actor. 

Study: Serotonin theory of depression wrong (antidepressants v placebo)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172306/

The serotonin theory is as close as any theory in the history of science to having been proved wrong. Instead of curing depression, popular antidepressants may induce a biological vulnerability making people more likely to become depressed in the future.

However, the overdiagnosis problem means that what we call ‘mild depression’ might just be the regular human blues and resolve itself.

The Depressive Personality and why the drugs don’t work (SSRIs)

http://charltonteaching.blogspot.co.uk/2015/06/modern-depression-and-bipolar-disorder.html

It becomes a handy excuse too.

Pop the pills, blame your condition for your failures….

Yes, that’s right.
It even has a clinical term I’m surprised Bruce Charlton doesn’t know/mention: the absolution of responsibility.
It used to be applied to the clinician, a duty of care, but increasingly it is discussed among overdiagnosis (a tragedy of the commons with prescriptions) issues and whether “patients” are embellishing or lying for instrumental gain (welfare, sympathy, an excuse to be a worthless piece of…. I digress).

Most would be better off with placebo pills, as TLP knows (where is she, anyone?). For example, they enjoy the idea they’re broken (hipsters) and hence nothing in/about their life is their fault (ignore the non-sequitur, I know). There is an escalation common in psychiatry, you start on the easy candy stuff like Ritalin and eventually it’s anti-psychotics, with the fun side effect of causing mass murder and shooting sprees you hear about on the news. This is also why feminists wish to drug little boys, it damages them for life and they think it’s revenge for the slutty ones ‘needing’ the Pill. Don’t expect logic.

Drugs should be a last resort, not as casual as an after-dinner mint. A single one begins irreversible changes in the brain. If you weren’t fucked up before, you will be. http://www.medicalnewstoday.com/articles/282784.php

http://www.youtube.com/watch?v=ETxmCCsMoD0

n.b. The chemical imbalance hypothesis is bollocks. Rarely it might apply but there are chemical tests (serotonin for example), as you can probably gather (and CSF, ouch) and those will only get better. It’s an easy theory that sounds scientific but it’s unfalsifiable. Everyone has chemicals. There is no normal pattern either. It’s like choosing introverts or extraverts. Apples and oranges. It ignores genetics and brain structure because Narrative.

How likely is it that a series of disparate imbalances of simple chemicals cause the exact same disorders and conditions as they’re set out purely in the latest DSM-V and ICD-10? It is more likely that I am a bisexual goat.

Take a look: http://www.priory.com/psych/ICD.htm
To this day, those error codes give me a headache.

The (depression) drugs don’t work

http://slatestarcodex.com/2014/07/07/ssris-much-more-than-you-wanted-to-know/

I always make sure to ask a hipster SJW which depression meds she/he is on. Always SSRIs.

Why don’t they work, you ask?
I’m so glad you did. You see, psychology likes to bullshit its way to any plausible sounding causation without doing the Real Science of actually, you know, testing it. Against other explanations. Or beyond correlations. So with the big ($$$) problems like the umbrella ‘depression’ (which now, thanks to lax diagnosis, basically everyone has) there are at least a few Big Causes to be repeated ad nauseum while they can milk it for sweet, sweet funding juice.

Depression pills work on the Chemical Cause hypothesis.
Party line: Mental illness is caused by a neurochemical imbalance in the brain. Note the underline, we’ll come back to it later.

Sure, the brain has neurochemicals. Sure, they can be out of balance (and right themselves again over time, long live control groups). But did you know a normal person taking said pills can have their neurochemistry irreversibly altered? So they require harder and harder ‘medicines’ up to anti-psychotics, the strongest class, taken For Life? Funny that. Also, note the number of spree killers who had a history of this drug escalation in their files. It isn’t gun control laws. It’s the drugs. They don’t work – the way they should. They do work, to worsen already unstable people into psychotic episodes.

If you’re interested in a Berlin psychiatrist’s perspective, this woman is one of my favourite writers.
http://thelastpsychiatrist.com/2008/12/major_depression.html
http://thelastpsychiatrist.com/2008/08/a_solution_to_the_pharma_probl.html
http://thelastpsychiatrist.com/2014/04/the_maintenance_of_certificati.html

Disclaimer: medications have their place IF i) they are thoroughly researched ii) they are correctly applied and iii) they are banned from people who do not demonstrate a need for them (hypochondriacs, drug-abusers and attention-seekers are more common to a psychiatrist than any other type of Doctor).

Why should I care, DS?
Because psychiatry is moving away from relatively harmless SSRIs (if you ignore the Prozac suicides) to the stronger stuff, anti-psychotics. If they can fuck up a schizophrenic, imagine what they can do to normal kids who came in through the door on the blatant BS of ADHD. Expect more shootings, or gorey school stabbings, even if all guns were banned, and other horrific crimes that will be passed off as Religion’s Fault. Did I mention most people brought into London’s prison system, also meet some criteria for schizophrenia? YupThe biology of these medications, and other drugs like ‘safe’ marijuana, are well known. They just don’t care.

To leave you with a brain teaser, consider this addendum to the QM study already cited;

Interestingly, there was no increase in risk of violence for untreated prisoners with delusional disorder. [control group, no drugs] Drug-induced psychosis was linked with a nearly twofold risk of violence following release, but this became non-significant following adjustments for drug and/or alcohol dependence**.

Do you understand more than the researchers now, given this article?

There is no free will in science

Our understanding of free will, in fact, was informed by theology. If you could choose how to act, religion could control you, the bread and the birch. Calvinists adopted the opposite position but still acted in accordance with scripture. Same goes for other ‘Chosen’ groups.

One day genetic engineering will prove us victors

Free will is antithetical to cause and effect. Billions of events occurred to bring us as organisms to this present moment in the universe, with our precise configuration of genes, chemicals and schemata. We may think we are choosing A over B over C, yet divorced from our personal involvement, it is easy to see which option a self-interested higher mammal will opt for on little biographical info.

Humans are predictable and the ever-dwindling excess margin is a measurement error.

Belief has an effect on outcomes, thusly it is a cause, but sustaining belief is an ability in itself (try telling that to atheists). Strength to strength, or character, as it was once known. Self-efficacy, the belief in oneself when acting, bolsters performance, in a type of outcome placebo effect.

Extremes are frowned upon by the average, it threatens them. Absolving responsibility is an outcome of misinterpretation. There is certainly responsibility for our actions, in spite of our changing understanding of choice, because we did them. Criminal responsibility requires actus reus, the act, and mens rea in many cases, the intention.

As both are present, we are not free but we are responsible.

It joins the ranks of other terrifying facts, shelved alongside precious mortality.