Paper: Pneumonic plague as bioweapon, signs

https://www.nejm.org/doi/full/10.1056/NEJMra1409755

In this article, we review the clinical management of deliberate infection with several pathogens of greatest bioweapons concern. On the basis of historical incidents coupled with information on ease of dissemination, contagiousness, mortality rates, public health impact, ability to engender panic, and the need for special preparedness,1-3 the Centers for Disease Control and Prevention (CDC) stratifies pathogens and toxins into three risk categories — A, B, and C — with category A meriting the highest level of concern and preparedness.4,5 In this review, we consider diseases that are caused by category A agents for which there are high-quality clinical data in the unclassified literature (see the Supplementary Appendix, available with the full text of this article at NEJM.org). The category A viral hemorrhagic fever viruses are beyond the scope of this review.

Pneumonic Plague

Pneumonic plague is caused by infection with the fleaborne bacterium Yersinia pestis. This organism, found worldwide and responsible for the “Black Death,” can cause several forms of illness: bubonic (the most common) (Figure 1D), septicemic, and pneumonic plague.41 Because of the focus of this review, only pneumonic plague is discussed.

How fucking fascinating.

CARDINAL FEATURES OF PNEUMONIC PLAGUE

In a deliberate attack, primary pneumonic plague — rather than secondary spread from bubonic or septicemic forms — would occur 1 to 3 days after inhalation of the released bacterium or after droplet transmission from another infected person. The initial presentation of pneumonic plague is nonspecific and is difficult to differentiate from an ordinary pneumonia in its early stages. Hemoptysis, a unique feature, might be present, and rapid progression to respiratory failure and death would occur with greater frequency than in ordinary pneumonias.41

I imagine this would make the death count impossible to distinguish from regular pneumonia.

Remember: “Hemoptysis, a unique feature, might be present…”

About that….

https://tribune.com.pk/story/2146154/1-coronavirus-scare-looms-karachi/

“Maintaining that the 2019-nCoV may cause mild to severe respiratory disease, initially clinically presented as fever, dry cough, myalgia (muscle pain), fatigue and gradually progressing to a more severe productive cough that produces phlegm, episodic headaches, hemoptysis (coughing up blood) and occasional diarrhoea.”

http://www.china.org.cn/china/Off_the_Wire/2020-01/26/content_75650590.htm

“About 55 percent of the patients developed dyspnoea. Less common symptoms were sputum production, headache, hemoptysis and diarrhea.”

https://www.msn.com/en-us/health/medical/is-it-a-cold-the-flu-or-coronavirus-how-to-tell-the-difference/ar-BBZzIsH

“Common coronavirus symptoms can include: — Fever — Dry cough — Shortness of breath — Aching muscles — Fatigue

Less typical coronavirus symptoms: — Phlegm buildup — Headache — Hemoptysis — Diarrhea ”

What PP is versus what we’re told CV is by the MSM.

“Hemoptysis, a unique feature…”

Why has nobody else done it this way? aka the empirical one

look at signs, look at symptoms

unique feature…

u n i q u e   f e a t u r e

I can’t be the only smartass.

But if I must.

DIAGNOSIS OF PNEUMONIC PLAGUE

Because the clinical features of pneumonic plague are nonspecific, diagnosis is largely based on the results of culture. Sputum, blood, or lymph-node aspirates could yield positive culture results. Chest radiography would reveal a severe pneumonic process. Serologic testing can also be useful but would not play much of a role during acute illness.41 Rapid antigen tests are available in regions in which plague is endemic, but none are FDA-approved.

Oh no!

So we’d see tests be useless early on…

and… a shortage of testing kits…

especially for America… who I imagine would call some state of emergency.

TREATMENT AND PREVENTION OF PNEUMONIC PLAGUE

The treatment of pneumonic plague involves a 10-day course of an aminoglycoside antibiotic agent, such as streptomycin or gentamicin. Doxycycline is considered a second-line treatment.41 However, a randomized, controlled trial of potential treatments for bubonic plague revealed equivalency between gentamicin and oral doxycycline; it is unclear whether these results can be extrapolated to pneumonic plague.42 There has been increased interest in the use of fluoroquinolones as primary treatment in mass-casualty settings.42 A 7-day course of doxycycline or ciprofloxacin would be used as postexposure prophylaxis.41 No vaccine against plague is available. Because pneumonic plague can be transmitted from person to person through respiratory droplets, droplet precautions must be implemented for all patients.41

Why do the Chicoms want disease-ridden people in hospitals that can supposedly do nothing for them?

https://www.medscape.com/viewarticle/500621_2

..supplemented with 10% fetal calf serum and penicillin/streptomycin. To make the quail QT6/ACE2 cell line, the gene encoding the receptor for SARS-CoV, human angiotensin-converting enzyme 2…

Rest behind a paywall. Great. It’s a 2005 paper about treating coronavirus.

https://www.nejm.org/doi/full/10.1056/NEJM199709043371004

Yersinia pestis is the causative agent of plague, a zoonotic disease transmitted to humans through flea bites and typically characterized by the appearance of a tender and swollen lymph node, the bubo. Human-to-human transmission can occur, through either the bite of fleas (bubonic plague) or respiratory droplets, causing an overwhelming infection called pneumonic plague.

Our history books missed out that part.

Suddenly those masks don’t look so stupid.

The last plague pandemic began in Hong Kong in 1894 and spread throughout the world, establishing many endemic foci. Antibiotics and enforcement of public health measures significantly decreased the morbidity and mortality associated with the disease but did not allow its eradication. In fact, plague is now considered a reemerging disease1 ….

We report high-level resistance to multiple antibiotics, including all the drugs recommended for plague prophylaxis and therapy, in a clinical isolate of Y. pestis. The resistance genes were carried by a plasmid that could conjugate to other Y. pestis isolates. This report should serve as a warning of the risk of the spread of resistance in Y. pestis, a species previously considered universally susceptible to antibiotics.

…Strain 17/95 was resistant not only to all the antibiotics recommended for therapy (chloramphenicol, streptomycin, and tetracycline) and prophylaxis (sulfonamides and tetracycline) of plague4 but also to drugs that may represent alternatives to classic therapy, such as ampicillin, kanamycin, spectinomycin, and minocycline. The isolate remained susceptible to cephalosporins, other aminoglycosides, quinolones, and trimethoprim, and treatment with trimethoprim, despite its lack of synergism with sulfonamides, most likely led to the patient’s recovery….

https://www.nejm.org/doi/full/10.1056/NEJMoa2001316

The initial cases of novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP.

LOL: https://www.theguardian.com/world/2019/nov/13/two-people-diagnosed-with-pneumonic-plague-in-china

identified by local hospitals using a surveillance mechanism for “pneumonia of unknown etiology” that was established in the wake of the 2003 severe acute respiratory syndrome (SARS) outbreak with the aim of allowing timely identification of novel pathogens such as 2019-nCoV.4 In recent days, infections have been identified in other Chinese cities and in more than a dozen countries around the world.5 Here, we provide an analysis of data on the first 425 laboratory-confirmed cases in Wuhan to describe the epidemiologic characteristics and transmission dynamics of NCIP.

Suspicious.

Furthermore, children might be less likely to become infected or, if infected, may show milder symptoms, and either of these situations would account for underrepresentation in the confirmed case count. Serosurveys after the first wave of the epidemic would clarify this question.

re Pneumonic plague above: “Serologic testing can also be useful but would not play much of a role during acute illness.”

If it looks like a duck, walks like a duck and quacks like a duck – sure, it could be a chicken in a duck suit for kinky reasons but I’m inclined on probability to call it a fucking duck.

delays to hospitalization were much longer, with 89% of patients not being hospitalized until at least day 5 of illness (Figure 2). This indicates the difficulty in identifying and isolating cases at an earlier stage of disease. 

re pneumonic plague, above: “The initial presentation of pneumonic plague is nonspecific and is difficult to differentiate from an ordinary pneumonia in its early stages.”

It’s the same hymn sheet. I can’t be the only one seeing this.

Our preliminary estimate of the incubation period distribution provides important evidence to support a 14-day medical observation period or quarantine for exposed persons.

re pneumonic plague, above: “In a deliberate attack, primary pneumonic plague — rather than secondary spread from bubonic or septicemic forms — would occur 1 to 3 days after inhalation of the released bacterium or after droplet transmission from another infected person.”
“The treatment of pneumonic plague involves a 10-day course of an aminoglycoside antibiotic agent, such as streptomycin or gentamicin. ”
“Because pneumonic plague can be transmitted from person to person through respiratory droplets, droplet precautions must be implemented for all patients.41

That takes about…. 14 days.

Our study suffers from the usual limitations of initial investigations of infections with an emerging novel pathogen, particularly during the earliest phase, when little is known about any aspect of the outbreak and there is a lack of diagnostic reagents.

re pneumonic plague: “The initial presentation of pneumonic plague is nonspecific and is difficult to differentiate from an ordinary pneumonia in its early stages.”

re pneumonic plague: “diagnosis is largely based on the results of culture”

Furthermore, the initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms, and an asymptomatic infection in a child has also been reported.17

https://www.cdc.gov/plague/symptoms/index.html

“Pneumonic plague: Patients develop fever, headache, weakness, and a rapidly developing pneumonia with shortness of breath, chest pain, cough, and sometimes bloody or watery mucous. Pneumonic plague may develop from inhaling infectious droplets or may develop from untreated bubonic or septicemic plague after the bacteria spread to the lungs. The pneumonia may cause respiratory failure and shock. Pneumonic plague is the most serious form of the disease and is the only form of plague that can be spread from person to person (by infectious droplets).”

That’s why hide it.

https://www.mayoclinic.org/diseases-conditions/plague/symptoms-causes/syc-20351291

“Pneumonic plague affects the lungs. It’s the least common variety of plague but the most dangerous, because it can be spread from person to person via cough droplets. Signs and symptoms can begin within a few hours after infection, and may include:

  • Cough, with bloody mucus (sputum)
  • Difficulty breathing
  • Nausea and vomiting
  • High fever
  • Headache
  • Weakness
  • Chest pain

Pneumonic plague progresses rapidly and may cause respiratory failure and shock within two days of infection. Pneumonic plague needs to be treated with antibiotics within a day after signs and symptoms first appear, or the infection is likely to be fatal.”

repeating coronavirus paper:

Although delays between the onset of illness and seeking medical attention were generally short, with 27% of patients seeking attention within 2 days after onset.

Complete coincidence.

Back to CV paper generally

Early infections with atypical presentations may have been missed, and it is likely that infections of mild clinical severity have been under-ascertained among the confirmed cases.18 We did not have detailed information on disease severity for inclusion in this analysis.

In conclusion, we found that cases of NCIP have been doubling in size approximately every 7.4 days in Wuhan at this stage. Human-to-human transmission among close contacts has occurred since the middle of December and spread out gradually within a month after that. Urgent next steps include identifying the most effective control measures to reduce transmission in the community. The working case definitions may need to be refined as more is learned about the epidemiologic characteristics and outbreak dynamics. The characteristics of cases should continue to be monitored to identify any changes in epidemiology — for example, increases in infections among persons in younger age groups or health care workers. Future studies could include forecasts of the epidemic dynamics and special studies of person-to-person transmission in households or other locations, and serosurveys to determine the incidence of the subclinical infections would be valuable.14

re Pneumonic plague above: “Serologic testing can also be useful but would not play much of a role during acute illness.”

These initial inferences have been made on a “line list” that includes detailed individual information on each confirmed case, but there may soon be too many cases to sustain this approach to surveillance, and other approaches may be required.19

Study allowed by Chinese Government, who arrested 8 doctors for trying to release some piece of information, can’t imagine what.

If they’d been told to give people antibiotics for a virus though, I imagine they had some pointed questions.

Especially if the Chicoms wanted to buy time to buy up global supply and produce more.

https://en.wikipedia.org/wiki/Pneumonic_plague

“Pneumonic plague is a severe lung infection caused by the bacterium Yersinia pestis. Symptoms include fever, headache, shortness of breath, chest pain, and cough. They typically start about three to seven days after exposure.”

Long lag time.

PP can cause meningitis, which might explain the headache.

from CV article above: “”Common coronavirus symptoms can include: — Fever — Dry cough — Shortness of breath — Aching muscles — Fatigue”

https://www.cdc.gov/coronavirus/about/symptoms.html

“For confirmed 2019-nCoV infections, reported illnesses have ranged from people with little to no symptoms to people being severely ill and dying. Symptoms can include:

  • Fever
  • Cough
  • Shortness of breath”

All three just so happen to be also the symptoms of pneumonic plague.

“CDC believes at this time that symptoms of 2019-nCoV may appear in as few as 2 days or as long as 14 after exposure”

So three, three days on the low end. How familiar.

About dat headache symptom…

Click to access 23064.pdf

Coronaviruses as Encephalitis

-Inducing Infectious Agents

so why is headache not described as a symptom?

also

“In acute encephalitis, viral replication occurs in the brain tissue itself, possibly causing destructive lesions of the
gray matter, as was described after herpes simplex virus (HSV), rabies, or some arbovirus infections. ”

Yes, herpes can reach the brain. Again, I must remind you. Yes, it can.

This concludes why I’m banned from appearing on tv (pretty much).

Video: UK disease vectors and plague

Reminder: applies to all infections, not just sexually exclusive ones.

The prohibition on sodomy also applied to sodomy with women for the same reasons. It’s the same exact act, normalised in Jewish entertainment.

Sexually, it’s always men who are the main vectors of any disease (for many reasons, including going out more, washing hands less). Until literally a few years ago, biologists assumed the male urethra was always clean (immunoprivileged, like the eyes) – until they actually checked it... Turns out no vital pipe is clean, if you’re being a slut (sorry, “sexually active”). Men are the main vectors of any condition, and with HIV, ebola, this obvious “corona” (really pneumonic plague*) virus going round, knowing who’d be the likeliest carrier socially could save your life.

R-types are known for being happy Typhoid Marys, it isn’t just bug chasing “gift givers”, they can consciously pass on lesser conditions from spite (usually homoerotic, so other men are largely at risk). Even with a simple stomach bug or a norovirus, they’ll have an impulse to “meet up with old friends” so delay those ‘invitations’ past the incubation window and they’ll suddenly lose interest.

(Borderline and sociopathic women also do this, but usually it’s men).

Making people sick gives them a thrill of power over your body. And it’s mostly legal (with certain STD exceptions, that are ABH here up to GBH dependent).

*The Chinese gov keeps writing COD as ‘pneumonia’ because it isn’t corona. It’s plague.

The Black Death came from Asia too. Do your research. This is why they refuse to share DNA with Australia – it isn’t corona. Just a theory, but it’s the only thing that fits their paranoia. COD docs are legally binding.

They never did find a cure for plague, it’s almost Biblical.

B-b-b-but muh appeal to authority?! – some moron

K.

https://www.nature.com/articles/s41541-020-0156-y

A few days ago:

Yersinia pestis, the cause of plague, could be weaponized.

Unfortunately, development of new vaccines is limited by lack of correlates of protection.

aka unlike other diseases, they can’t pump out a plague vaccine on the pipeline

We used pre- and post-vaccination sera and peripheral blood mononuclear cells from a flagellin adjuvanted F1/V vaccine trial to evaluate for protective markers. Here, we report for the first time in humans that inverse caspase-3 levels, which are measures of protective antibody, significantly increased by 29% and 75% on days 14 and 28 post-second vaccination, respectively. In addition, there were significant increases in T-cell responses on day 28 post-second vaccination. The strongest positive and negative correlations between protective antibody levels and gene expression signatures were identified for IFNG and ENSG00000225107 genes, respectively. Flagellin/F1/V subunit vaccine induced macrophage-protective antibody and significant CD4+ T-cell responses. Several genes associated with these responses were identified that could serve as potential correlates of protection.

Paper for compulsory vaccination… just like Spanish Flu.
Fun fact: Most of those who died were vaccinated.

But wait, why would you need a vaccine for a bacterial infection?

Don’t ask questions citizen, just take the injection.

nytimes.com/2019/11/13/world/asia/plague-china-pneumonic.html

Pneumonic Plague Is Diagnosed in China

Memoryhole absolut.

EARLY NOVEMBER, 2019.

It turns out, I have been researching this stuff for my health.

The Twenties are gonna be funny.

What would happen to their economy if we knew the truth?

Even if it were coronavirus:

https://www.nejm.org/doi/10.1056/NEJMc2001468

The novel coronavirus (2019-nCoV) from Wuhan is currently causing concern in the medical community as the virus is spreading around the world.1 Since its identification in late December 2019, the number of cases from China that have been imported into other countries is on the rise, and the epidemiologic picture is changing on a daily basis. We are reporting a case of 2019-nCoV infection acquired outside of Asia in which transmission appears to have occurred during the incubation period in the index patient.

Asymptomatic, Typhoid Mary types.

Late December 2019.

You know what spreads great during the invisible stage? Plague. Just sayin’.

What’s more likely? A disease magically changes on an almost daily basis* – or the Chicoms are lying?

*According to the NEW ENGLAND JOURNAL OF MEDICINE, redditfags! They’re throwing shade in academese.

I hate being smarter than everyone but I waited for them to release the truth, sportingly, and they didn’t so screw you, China.

 

[#~*intermission*~#]

 

If AA wants a wild ride, check homosexual studies of paraphilia if you can find them – inc. sadism (especially rape, interest in actual rape), cross-dressing, pedophilia (attraction to minors) and bestiality. When surveyed, interest in death and necrophilia is also reported but it’s hard to find that stuff online. Most serial killers are homosexual. (and also circumcised)

WHO fails biology

http://who.int/mediacentre/news/releases/2018/end-plague-madagascar/en/

These people don’t understand biology. You don’t keep the carriers alive.

It’s like fucking for virginity.

You keep it contained and let those would die anyway, go quietly.

It’s interesting because the original plague came from Asia.

Europe only caught it thanks to the mercantile trade.

Human vectors are contagious for at least a week, they claim.

You can circle the world a few times with modern technology.

Technology is usually the downfall of civilization because people expect it will “save” them from stupid decisions.

They are giving it ample opportunities to evolve increased virulence.

Observe, only an r-type could go to the centre of an outbreak of deadly disease, and happily meet up, shaking hands and sharing air with survivors and their families.

Plague bad – Science

https://medicalxpress.com/news/2017-11-health-madagascar-plague-outbreak.html

“A large outbreak of plague, including the rare form known as pneumonic plague, has health officials in Madagascar working to prevent the bacterial infection from spreading to neighboring countries. The World Health Organization (WHO) says there have been more than 1,800 confirmed, probable or suspected cases of plague since Aug. 1, including 127 deaths.
Dr. Pritish Tosh, an infectious diseases specialist at Mayo Clinic says, “Public officials are concerned about this going on in Madagascar and potentially moving to neighboring areas. At this point, I think it’s unlikely that this is going to go much farther beyond that just because by the time people are able to transmit, they are pretty sick.””

I think it’s unlikely – thank you, official science people!

Note something in common with the recent form of Ebola – airborne transmission.

What circulates on a flight?

All these diseases are evolving beyond bodily fluids and physical contact.
They’re atomising between their human ‘vectors’.

Obviously this has been predicted, ever since Malthus but by states too.
https://disenchantedscholar.wordpress.com/2014/06/02/reading-global-strategic-trends-2007-2036-document/
I singled out a passage on the subject, it was so overt.

“A major pandemic may be the instrument that causes a reverse in the process of globalization as national responses to contain infection will involve significant restrictions on personal mobility and interaction over a lengthy period. Some states may even be destabilized by the effort and resources required to address the situation””

Well, it wouldn’t be the worst thing.

It’s almost like borders formed for a reason. Same reason we used to trebuchet plague-ridden bodies into our enemys’ fortresses.

This is how we do things in Europe.
https://contagions.wordpress.com/2012/06/28/plague-at-the-siege-of-caffa-1346/
https://wwwnc.cdc.gov/eid/article/8/9/01-0536_article

White people. Bitchier than yow.

Humans are still evolving. Duh.

article here;

“Historically, the birthing process has limited brain size, because babies’ heads had to fit through the birth canal.

Today, however, Caesarian sections circumvent that process. As many as 46 percent of babies born today in China are delivered via C-section, Pobiner said. With advances in fertility and better postnatal medical care, she asked, “Are we screwing with natural selection?” [DS: yes]

The world population is growing, and a bigger population also evolves faster, Pobiner said. But, with rising sea levels and less land available, waterborne and airborne illness could spread more easily [global plague], Pobiner said.

The largest virus ever found was a virus thawed from permafrost, known as Pithovirus. While this parasite doesn’t infect humans, what if other ancient viruses thaw out that are harmful? [then non-Europeans will die] For example, the smallpox virus was eradicated in 1979, according to the World Health Organization, but some experts say it has only been eradicated from the Earth’s surface, surviving instead in frozen form. [diseases evolve too]

And human evolution persists in other areas too, such as sexual selection. A recent study found that beards become more attractive when they’re rare in a population. When “peak beard” is reached, they become less attractive, the study found. Economic conditions may also influence beardedness, as unemployed men may use beards as a sign of masculinity, Pobiner said.”