Men lose Y-chromosome with age

https://www.sciencedaily.com/releases/2016/05/160523212527.htm
That’s why they die earlier.

Really.
Stop blaming women and ‘sexism’, we aren’t omnipotent gene meddlers.
Also, genetic proof of a male wall. LOL. An explanation to why so many middle-aged men suddenly look like lesbians.

[coughs in Bruce Jenner]

And there’s no way to reverse it, before the snake oil salesmen jump up with a solution that, if it worked, would make them a billionaire.

Nobel winner.

World famous.

Popping pills to get out of laziness is what lefties do.

Bold for the lazy.

Using new tools to analyze genetic variations that accumulate with age, we can help explain how sporadic diseases like cancer or Alzheimer’s manifest,” says first author Jan Dumanski.

One such postzygotic mutation found in the cells of biological males is the loss of the Y chromosome in a degree of blood cells. Loss of Y occurs in up to 17 percent of men and is more likely to be found in older men and men who smoke. This study expands on the idea that loss of Y, already a known risk factor for cancer (10.1038/ng.2966), could be a predictive biomarker for a wider range of poor health outcomes, specifically Alzheimer’s. Why loss of Y can be linked to an increased risk for disease remains unclear, but the authors speculate it has to do with reduced immune system performance.

They should look at age groups of men.

And diet.

IMHO.

The researchers looked at over 3,000 men to ascertain whether there was any predictive association between loss of Y in blood cells and Alzheimer’s disease. The participants came from three long-term studies that could provide regular blood samples: the European Alzheimer’s Disease Initiative, the Uppsala Longitudinal Study of Adult Men, and the Prospective Investigation of the Vasculature in Uppsala Seniors. Across the datasets, those with the highest fraction of blood cells without a Y chromosome were consistently more likely to be diagnosed with Alzheimer’s.

….Really more of an outcome of poor genetic health….

Did you test for aluminium?

Attempt chelation therapy?

Yeah, fuck the easy solution, blame the Y chromosome.

Like women don’t get it.

“Having loss of Y is not 100 percent predictive that you will have either cancer or Alzheimer’s,” Forsberg says, adding that there were men in the study who had the mutation and lived with no symptoms well into their 90s.

Were their fathers older or younger?

If paternal age is a factor in ANYTHING, it’s a risk factor for this.

Male chromosome plus mutation. Come on.

Men think they can fool women but white hairs on a ballsack don’t lie.

“But in the future, loss of Y in blood cells can become a new biomarker for disease risk and perhaps evaluation can make a difference in detecting and treating problems early.”

No shit.

Forsberg, Dumanski, and colleagues will next investigate the effect of loss of Y in larger cohorts and explore in greater detail how it confers risk for specific types of cancers and disease. They also plan to look at the cellular changes caused by loss of Y and how it affects different types of blood cells.The researchers looked at over 3,000 men to ascertain whether there was any predictive association between loss of Y in blood cells and Alzheimer’s disease. The participants came from three long-term studies that could provide regular blood samples: the European Alzheimer’s Disease Initiative, the Uppsala Longitudinal Study of Adult Men, and the Prospective Investigation of the Vasculature in Uppsala Seniors. Across the datasets, those with the highest fraction of blood cells without a Y chromosome were consistently more likely to be diagnosed with Alzheimer’s.”

Should look at heart disease, primary killer of American males.

But that’s none of my business.

If men aged well, they wouldn’t need to be on supplements.
Young men on supplements is just sad, like young women getting plastic surgery.
There’s no room to move. If you can’t be all that young, what are they going to do?
Our society treats aging like cancer, it’s ridiculous Boomer youth cult propaganda to sell them supplements like detox tea and testosterone ball rub. You can’t fool mother nature.

When they actually hit middle-age, they won’t be able to keep up with that crap anyway.
Imagine most of your shallow friends disappearing because you dropped the massive timesink of gym addiction.
The Ken Doll homoerotic gym attention bros look sad after about 40.

Plus bodybuilder types know there are two types of muscle: appearance and strength.
Guess which one they all go for?

The one that instantly converts to stubborn fat if they so much as look at a complex carbohydrate past 30.

The Johnny Bravo look is actually, industry secret, physically weak.

In a fight, any martial artist will tell you the bulk limits their range of motion like a fatty anyway.

All men need is a healthy range of light muscle, which women prefer but don’t require any supplement sales.
Light muscle also provides cognitive benefits with no musculoskeletal downsides, including sag and joint pain.
Bruce Lee could take a Henry Cavill any day of the week.

With the T&A they have a woman’s hourglass in profile, they gay.

At least, appealing to that market…..

Fornication discouraged in men, 1892

I don’t like it when SJWs lie about sexuality and pretend men could be the biggest sluts they wanted, forever, without consequence.
I don’t like it when men lie about their historic sexual habits either. There’s no excuse.

I was going to quote but screencaps deter liars. This was the common opinion and backed by the doctors of the time. They just can’t stand the idea their ancestors would be ashamed of them and think of them as just as slutty as the women they insult.

I guess their red pill got stuck?

Continence (sexual control) and sexual hygiene were the rule throughout history, we hear about exceptions because they were exceptions.

(And rich, usually rich and insane, it’s still fun to read about those).

https://wellcomelibrary.org/item/b28050964#?c=0&m=0&s=0&cv=0&z=-0.6656%2C0.8599%2C2.8112%2C1.4224

Act like a savage, think like one. Pretty straightforward. Lust isn’t a virtue for men either. Giving in to any desire is a huge display of weakness.

The energy is meant to go to your development. Wasting it elsewhere stunts growth permanently. Degenerate is quite a physical phenomena. If you took identical twins, one would be taller, better-looking and healthier for abstaining compared to a profligate twin.

It does stunt the growth, they’re right. Neuroscience is finding (supernormal) stimulation is really, really bad for you, especially if you’re still developing – the development time is cut prematurely short because the energy gets burnt up. You have a finite supply. Puberty is meant to take many years. Telling men to masturbate, that it’s good for them, might be the first nail in the masculine coffin (same applies for women).

A retardation of your mature sex’s qualities. It’s horrendous.

The best-looking and sounding men I’ve ever seen simply had no desire to masturbate as teenagers (they were busy doing other things). They turned out really well, the so-called “late bloomer” just used to be… normal. By comparison, we all know plenty of people who peaked physically age fifteen then weirdly aged at speed.

Guess what they have in common.

It’s also no coincidence the best geniuses are virgins.

To this day, the life outcomes of those with impulse control are superior, including general health.

Suck on that.

If you want a biological mechanism for this, look into how caloric restriction works. Your body has finite life processing power. Don’t waste it.

Most self-help books for men came in the form of morality lessons.
https://archive.org/details/dangersignals00clar
https://archive.org/details/advicetoyoungmen01cobb

Because they needed it.

No man is beyond reproach.

Video: What is a thot? (plus traps)

Okay, the joke’s over, it’s mainstream.

It’s the female version of a fuckboy, a trashy slut.

Note the age on this video. Like a wine*. You could’ve checked Urban Dictionary …but no.
Yeah, the alt right’s been stealing black slang. They’re just applying it to basic bitches, and even recently, normal and good women. I’ve mentioned how dumb it is to criticize women who don’t wanna be fat and useless, as the sex that hates fat and uselessness. Use basic bitch, it’s a good insult but ya gotta know for an insult to work, it needs to apply.
Everyone takes selfies now. Men take the most selfies down the gym – they thots? That’s the grammatically accurate use of the term. The standard for pop culture was that dog filter. I mean, damn, that dog filter. THOT-QED right there. Tindr? Thot. Female? Not a thot. It ain’t a synonym. Wearing a short skirt? Not a thot, normal in the West. Fashion is not a behaviour. Some of the sluttiest women dress modestly to get away with it, I’ve seen it. Club sluts, female club sluts. THOT – in da club.
He also discussed traps.

Look at the DATE. Stop nabbing ghetto culture and still insulting everything about them. You clearly liked some of it.
So technically, plenty of men posting gym selfies are thirsty traps. They’re attention-whoring for orbiters.
If you wanna use the tranny definition, just be specific. They’re copying black girls. A lot of black men secretly cross-dress. Like, a LOT. If you ask around. A LOT.

inb4*”Men age like wine.”

You can tell they don’t drink wine.

Sure, men age like wine. With each passing year, the odds of being infected and ruined forever increase exponentially. (called ‘corked’ wine)

“Asians age really well”

Alternate title: Asian women age the best.

Spoken by someone who has never seen elderly Asian women.

Not to be mean, but they age worse. So much worse.
Go to a beach or look up photos of elderly Asian women on the beach if you dare.

Bikini shots if ya got em.

then there’s this ridiculous propaganda that a 49-year old can look like a 19-year old

ever

pull the other one


this applies somewhat, deceptive considering the amount of makeup and surgery, but yes menopause is the ticker

also, nada about Indians, Chinese, Pakistanis, Afghanis etc etc.

AKA most of the Asians

Recently seen a trend for Greeks and Indians. Imagine how hairy the kids omg…

Ah, this one’s familiar. The public sour expression as they tolerate the beta males because they want half-white babies. They rarely see it but everyone else does, usually as a flicker when he speaks.

When they discuss how white women age, they always go for the anorexic ones.

Not to mention bad shots of makeup, close-up, when non-whites are at a distance with better make-up.

e.g.

https://www.thestudentroom.co.uk/showthread.php?t=3708515
User ‘Black is beautiful’ asks: Why do white women age in dog years?
No bias, I’m sure.
No jealousy, certainly.
Try starting a thread asking why non-white women are so morbidly obese, even when vegetarian. That should be fun.

r/K in old stories

Nowadays in a story of Kallikak, we’d have to include epigenetic inheritance from the venereal disease-ridden microbiome of the parents. Contrary to popular belief, recent findings have shown the male urethra does have a microbiome and is not sterile i.e. it passes to the mother during conception.

‘Two paths’ has two versions and few people are intellectually honest to include both.
The ages are off though.

In a patriarchy, men are held to sterner standards than women.

Have you ever noticed people with bad morals look older and more haggard?

Link: The Male Wall

http://simpleguyskills.com/male-physical-attractivenessaging/

Mark Paul Gosselar is someone who was in his prime much earlier in life. The first pic of Gosselar is him at age 19 and the second one is him at age 28. As you can see, he’s well past his prime at age 28.

Chances are, though, unless you inherited genes like Tom Cruise’s, Tom Brady’s, or Brad Pitt’s, if you’re past 35, you’re most likely past your prime in looks.

32 was the age I figured for the best genetic specimens.

Wow, I’m impressed to see helpful information on this topic than yet another silly wine quote.

Wines spoil too. Well, rot, actually. Men have a need to settle down in their physical peak too, unless they mistakenly believe they’re Peter Pan. The male sexual peak is 18 according to sexology. Such males like to say the male peak is middle age. Convenient, considering that’s all they have left to snag a wife.

Let’s take a prime example.

Brad Pitt.

Age, spot the physical peak.

Simply search <name> <year> to try it with others.

in 1991

in 1997

in 1999

in 2001

in 2003

in 2005

 

in 2013

in 2015

Don’t trust your lying eyes. It’s like fat acceptance, they think if they repeat it often enough, it’ll make them hot.